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Modeling The Influence Of Vibration On Flow Through Embedded Microchannels, Joseph S. Seamons
Modeling The Influence Of Vibration On Flow Through Embedded Microchannels, Joseph S. Seamons
Theses and Dissertations
The influence of vocal fold (VF) vibration on perfused flow through VF vasculature is an area of research that has previously received limited attention. The aim of the research presented in this thesis was to contribute towards an improved understanding of the effects vibration on perfusion through vasculature within the VFs. This was done using a series of computational simulations of geometric changes to, and perfusion through, microchannels embedded in VF models. A computational structural model based on synthetic VF models used in previous experimental studies was first developed. The model and its embedded microchannel were initially studied under static …
Perfusion Pressure-Flow Relationships In Synthetic Poroelastic Vocal Fold Models, Cooper B. Thacker
Perfusion Pressure-Flow Relationships In Synthetic Poroelastic Vocal Fold Models, Cooper B. Thacker
Theses and Dissertations
The purpose of this research was to study perfusion pressure-flow relationships in self-oscillating synthetic poroelastic vocal fold (VF) models before, during, and after vibration. This was accomplished by developing a custom ultra-soft poroelastic material, incorporating the poroelastic material as the cover layer in a synthetic VF model, and studying the model vibratory response and the flow rate of fluid perfused through the cover layer while undergoing flow-induced vibration. The custom ultra-soft poroelastic material was developed using the method of direct templating with sucrose spheres as the sacrificial template and silicone as the infiltration medium. The average modulus of elasticity of …