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Articles 1 - 30 of 91
Full-Text Articles in Engineering
Effect Of Antioxidant Additives And Recycling Agents On Performance Of Asphalt Binders And Mixtures - Phase I, Nitish R. Bastola, Mahdieh Khedmati, Hamzeh Haghshenas, Jamilla Teixeira
Effect Of Antioxidant Additives And Recycling Agents On Performance Of Asphalt Binders And Mixtures - Phase I, Nitish R. Bastola, Mahdieh Khedmati, Hamzeh Haghshenas, Jamilla Teixeira
Nebraska Department of Transportation: Research Reports
The use of reclaimed asphalt pavement (RAP) in asphalt mixtures has notably increased in recent times. Nevertheless, the inherent stiff and aged characteristics of RAP materials have consistently raised concerns regarding cracking performance. The use of recycling agents (RAs) has gained popularity in recent years since they can effectively modify the engineering properties of the aged asphalt binder. Besides that, the combination of RA with antioxidant (AO) additives has shown promise in enhancing the long-term performance of RAP mixtures. This research aims to investigate the effect of various RAs and one AO additive on performance of asphalt binders and high-RAP …
Surface Treatments' Effects On The Capacitor's Dielectric Performance Under Electro-Thermal Stresses, Haider. M. Umran, Feipeng Wang
Surface Treatments' Effects On The Capacitor's Dielectric Performance Under Electro-Thermal Stresses, Haider. M. Umran, Feipeng Wang
Karbala International Journal of Modern Science
Biaxial-oriented polypropylene (BOPP) films are characterized by unfavorable aging behavior because of their poor susceptibility to high temperatures, humidity, and high electric fields. This makes them unqualified to withstand harsh operating conditions, such as in capacitor applications. This study investigates the impact of annealing BOPP samples at 100 °C for five hours after fluorination at different times (15, 30, and 60 minutes) on their electrical and mechanical performance under electro-thermal stresses. Scanning electron microscope (SEM) images confirm that there is an increase in surface roughness and the formation of a dense layer of fluorine-containing groups monotonically with fluorination time. So, …
Quantifying Balance: Computational And Learning Frameworks For The Characterization Of Balance In Bipedal Systems, Kubra Akbas
Quantifying Balance: Computational And Learning Frameworks For The Characterization Of Balance In Bipedal Systems, Kubra Akbas
Dissertations
In clinical practice and general healthcare settings, the lack of reliable and objective balance and stability assessment metrics hinders the tracking of patient performance progression during rehabilitation; the assessment of bipedal balance plays a crucial role in understanding stability and falls in humans and other bipeds, while providing clinicians important information regarding rehabilitation outcomes. Bipedal balance has often been examined through kinematic or kinetic quantities, such as the Zero Moment Point and Center of Pressure; however, analyzing balance specifically through the body's Center of Mass (COM) state offers a holistic and easily comprehensible view of balance and stability.
Building upon …
Optimizing Laboratory Curing Conditions For Hot Mix Asphalt To Simulate Field Behavior, Benjamin Arras
Optimizing Laboratory Curing Conditions For Hot Mix Asphalt To Simulate Field Behavior, Benjamin Arras
Open Access Theses & Dissertations
The engineering properties of asphalt mixtures change with time. Shortly after placement, asphalt concrete (AC) layers are more susceptible to rutting. As the pavement ages, the AC layer becomes stiffer, brittle, and thus more susceptible to cracking. Current protocols provide guidelines for the selection of materials, the determination of the material proportions (e.g., aggregates and binder content), and the evaluation of the engineering properties (e.g., cracking and rutting potentials) of any given asphalt mix design. However, these protocols do not consider the impact of aging on the mixture. This study investigated existing and novel laboratory methods to determine protocols that …
Assesment Of Structure, Function, And Microevolutionary Dynamics Of Extrachromosomal Circular Dna In Chinese Hamster Ovary Cells, Dylan Chitwood
Assesment Of Structure, Function, And Microevolutionary Dynamics Of Extrachromosomal Circular Dna In Chinese Hamster Ovary Cells, Dylan Chitwood
All Dissertations
Chinese hamster ovary (CHO) cell lines are among the most popular expression hosts used in biopharmaceutical manufacturing due to relative ease of culture, capacity to perform human-like post-translational modifications, and non-susceptibility to viruses. However, the intrinsic plasticity of the CHO genome can lead to undesired genetic rearrangements, phenotypic shifts, reduced product quality, and early culture termination that prevents continuous biomanufacturing. A characteristic of plastic and unstable genomes that is poorly understood in CHO cells is extrachromosomal circular DNA (eccDNA). EccDNAs are focal amplifications of the genome that reside in the extranuclear space. These plasmid-like entities are structurally complex and are …
A Bibliometric Analysis And Review On The Performance Of Polymer-Modified Bitumen, Adham M. Alnadish, Herda Y. B. Katman, Mohd R. Ibrahim, Yaser Gamil, Nuha S. Mashaan
A Bibliometric Analysis And Review On The Performance Of Polymer-Modified Bitumen, Adham M. Alnadish, Herda Y. B. Katman, Mohd R. Ibrahim, Yaser Gamil, Nuha S. Mashaan
Research outputs 2022 to 2026
The addition of polymer to a base binder has been documented as a successful approach in terms of improving physical and rheological properties of the base bitumen. However, the main drawbacks of polymer-modified bitumen are incompatibility and degradation of polymer due to aging. This article aims to introduce a bibliometric analysis and review on modifying bitumen with polymers. Additionally, this article intent to highlight the significant gaps and recommendations for future work. Furthermore, another objective of this article is to provide a worth attempt regrading reducing the negative impact of polymer’s drawbacks on the performance of polymer-modified base binder. The …
A Comparison Of Feature Selection Methodologies And Learning Algorithms In The Development Of A Dna Methylation-Based Telomere Length Estimator, Trevor Doherty, Emma Dempster, Eilis Hannon, Jonathan Mill, Richie Poulton, David Corcoran, Karen Sugden, Ben Williams, Avshalom Caspi, Terrie E. Moffitt, Sarah Jane Delany, Therese Murphy Dr
A Comparison Of Feature Selection Methodologies And Learning Algorithms In The Development Of A Dna Methylation-Based Telomere Length Estimator, Trevor Doherty, Emma Dempster, Eilis Hannon, Jonathan Mill, Richie Poulton, David Corcoran, Karen Sugden, Ben Williams, Avshalom Caspi, Terrie E. Moffitt, Sarah Jane Delany, Therese Murphy Dr
Articles
The field of epigenomics holds great promise in understanding and treating disease with advances in machine learning (ML) and artificial intelligence being vitally important in this pursuit. Increasingly, research now utilises DNA methylation measures at cytosine–guanine dinucleotides (CpG) to detect disease and estimate biological traits such as aging. Given the challenge of high dimensionality of DNA methylation data, feature-selection techniques are commonly employed to reduce dimensionality and identify the most important subset of features. In this study, our aim was to test and compare a range of feature-selection methods and ML algorithms in the development of a novel DNA methylation-based …
Fundamental Investigation Of Interaction Between Moisture And Asphalt-Aggregate Systems, Rui Xiao
Fundamental Investigation Of Interaction Between Moisture And Asphalt-Aggregate Systems, Rui Xiao
Doctoral Dissertations
Moisture-induced damage is one of the most common forms of flexible pavement distress which directly causes or exacerbates pavement failure. The intrusion of moisture into the asphalt pavements reduces the overall mechanical properties of the locking structures and gives rise to one or more of the visible forms of distress such as raveling, stripping, permanent deformation and fatigue cracking. This doctoral study is aimed at understanding the detrimental action of water on the asphalt-aggregate systems and the damage mechanism by multi-technique investigation. A thermodynamics framework was considered to characterize the properties of asphalt mix ingredients as well as the engineering …
Musculoskeletal Adaptation Of Young And Older Adults In Response To Challenging Surface Conditions, Amy E. Holcomb, Nicholas L. Hunt, Amanda K. Ivy, Aidan G. Cormier, Tyler N. Brown, Clare K. Fitzpatrick
Musculoskeletal Adaptation Of Young And Older Adults In Response To Challenging Surface Conditions, Amy E. Holcomb, Nicholas L. Hunt, Amanda K. Ivy, Aidan G. Cormier, Tyler N. Brown, Clare K. Fitzpatrick
Mechanical and Biomedical Engineering Faculty Publications and Presentations
Over 36 million adults over 65 years of age experience accidental falls each year. The underlying neuromechanics (whole-body function) and driving forces behind accidental falls, as well as the effects of aging on the ability of the musculoskeletal system to adapt, are poorly understood. We evaluated differences in kinematics (lower extremity joint angles and range of motion), kinetics (ground reaction force), and electromyography (muscle co-contraction), due to changes in surface conditions during gait in 14 older adults with a history of falling and 14 young adults. We investigated the impact of challenging surfaces on musculoskeletal adaptation and compared the mechanisms …
Vibrotactile Perception For Sensorimotor Augmentation: Perceptual Discrimination Of Vibrotactile Stimuli Induced By Low-Cost Eccentric Rotating Mass Motors At Different Body Locations In Young, Middle-Aged, And Older Adults, Ella Pomplun, Ashiya Thomas, Erin Corrigan, Valay A. Shah, Leigh A. Mrotek, Robert A. Scheidt
Vibrotactile Perception For Sensorimotor Augmentation: Perceptual Discrimination Of Vibrotactile Stimuli Induced By Low-Cost Eccentric Rotating Mass Motors At Different Body Locations In Young, Middle-Aged, And Older Adults, Ella Pomplun, Ashiya Thomas, Erin Corrigan, Valay A. Shah, Leigh A. Mrotek, Robert A. Scheidt
Biomedical Engineering Faculty Research and Publications
Sensory augmentation technologies are being developed to convey useful supplemental sensory cues to people in comfortable, unobtrusive ways for the purpose of improving the ongoing control of volitional movement. Low-cost vibration motors are strong contenders for providing supplemental cues intended to enhance or augment closed-loop feedback control of limb movements in patients with proprioceptive deficits, but who still retain the ability to generate movement. However, it remains unclear what form such cues should take and where on the body they may be applied to enhance the perception-cognition-action cycle implicit in closed-loop feedback control. As a step toward addressing this knowledge …
Alpha Synuclein: A Therapeutic Target And Biomarker For Parkinson’S Disease, Max Chase
Alpha Synuclein: A Therapeutic Target And Biomarker For Parkinson’S Disease, Max Chase
USF Tampa Graduate Theses and Dissertations
Parkinson’s Disease is the second most common neurodegenerative disease after Alzheimer’s Disease, and the most common motor disorder. In fact, nearly a third of those with AD have PD. A major hallmark of PD is the appearance of Lewy Bodies, proteinaceous cytoplasm inclusions, that build up and spread throughout the CNS in a prion like fashion. The major component of these Lewy Bodies is a protein called alpha-synuclein. Alpha-syn is a 14kDa protein made of 140 amino acids and found in the presynaptic ends of CNS neurons, acting as a chaperone and regulator. The protein is also found in the …
Multi-Task Neuromuscular Generalization And Changes Through The Lifespan, Hannah Delaney Carey
Multi-Task Neuromuscular Generalization And Changes Through The Lifespan, Hannah Delaney Carey
Graduate Theses, Dissertations, and Problem Reports
Mobility in everyday life requires executing and shifting between a broad assortment of functional tasks and resisting disturbances that could cause falls. Though the importance of successfully performing a variety of functional tasks is recognized and incorporated in clinical assessments (e.g., the Timed-Up-and-Go Test, Berg Balance Scale), little is understood about the underlying neuromuscular control required, or how it changes with age. The neuromuscular control for functional tasks such as walking is typically studied in isolation, or with variations on the same task. Characterizing the coordination required to produce and shift between a wider variety of tasks and resist external …
The Development Of A Novel Blood-Brain Barrier, Organ-On-A-Chip System And The Identification Of Erythrocytes As A Key Contributor To Age-Associated Neurological Decline, Payam Amiri
KGI Theses and Dissertations
Advancements in modern medicine have greatly extended human life expectancy. However, with the onset of age-associated conditions such as Alzheimer’s disease, autoimmune disorders, and certain cancers, healthy aging is becoming an increasingly pressing issue. Blood exchanges between young and old partners demonstrate old blood can cause detrimental effect to the young animal, notably on the brain tissue. However, the complexity of blood makes it difficult to identify what role the individual factors play in the aggregate observed effect. This dissertation seeks to explore the potential effects of erythrocytes on the brain as we age. Erythrocyte morphology and rigidity changes as …
Understanding The Underlying Mechanism Of Age-Related Underactive Bladder And Proposing A Treatment Option To Mitigate Its Symptoms, Arezoo Gerami Pour
Understanding The Underlying Mechanism Of Age-Related Underactive Bladder And Proposing A Treatment Option To Mitigate Its Symptoms, Arezoo Gerami Pour
FIU Electronic Theses and Dissertations
The prevalence of underactive bladder (UAB) increases with age, suggesting a link between age-related processes and lower urinary tract (LUT) symptoms; however, the underlying mechanisms of age-related UAB are poorly understood. UAB is characterized by inefficient voiding and bladder overdistension. Due to the unknown etiology, current therapeutic options are insufficient. Thus, a detailed understanding of its mechanism will facilitate the discovery of new treatments.
In Aim 1, we investigated the relationship between age and systems-level function of the LUT reflexes in three age groups of rats, testing the hypothesis that aging causes voiding reflexes to weaken. We systematically investigated the …
The Role Pde11a4 Signaling And Compartmentalization In Social Behavior, Kaitlyn Pilarzyk
The Role Pde11a4 Signaling And Compartmentalization In Social Behavior, Kaitlyn Pilarzyk
Theses and Dissertations
People tend to be social by nature. Being socially connected not only helps people live longer and healthier lives, but being an engaged and contributing member of society strengthens our communities overall. Maintaining intact social behaviors is key to maintaining this wellbeing, with disruptions negatively affecting both mental and physical health. Indeed, social isolation and feelings of loneliness can significantly increase a person’s risk of premature death, heart disease, and stroke as well as depression, anxiety, suicide, and dementia. Maintaining the ability to create and store social memory with age is, therefore, key to maintaining proper social behaviors. Unfortunately, individuals …
Musculoskeletal Adaptation Of Young And Older Adults In Response To Environmental, Physical, And Cognitive Conditions, Amy E. Holcomb
Musculoskeletal Adaptation Of Young And Older Adults In Response To Environmental, Physical, And Cognitive Conditions, Amy E. Holcomb
Boise State University Theses and Dissertations
Accidental falls present a large functional and financial burden among people aged 65 years and older. Falls, injuries associated with falls, and the fear of falling decrease quality of life, physical function, and independence for older adults. To prevent falls, improve stability, and protect joints from damage or injury, the typical response to "challenging" conditions include cautious gait, increase muscle co-contraction, and decreased range of motion. These compensatory strategies are more pronounced in the older adult population with apprehensive "cautious" gait at slower speeds, decreased knee flexion, and increased muscle activation around the knee and ankle. The underlying mechanisms and …
A Laboratory Investigation Of High Polymer Modified Asphalt Mixtures With Softening Agent, Basel K. Al-Badr
A Laboratory Investigation Of High Polymer Modified Asphalt Mixtures With Softening Agent, Basel K. Al-Badr
Theses and Dissertations
This study was initiated to evaluate the impact of aging and High Polymer Modified Asphalt (HPMA) binders containing a bio-based-oil softening agent (SA) on the rutting, cracking, and durability of asphalt mixtures. One control asphalt binder (PG 52-34), Styrene-Butadiene-Styrene (SBS) polymer modifier, and corn-oil SA were used to produce four asphalt mixtures including a control prepared using PG 52-34 binder and three modified mixtures were produced by blending PG 52-34 binder with different dosages of SBS and SA. The mixtures were tested using the Dynamic Complex Modulus (|E*|), Hamburg Wheel Tracking Device (HWTD), Flow Number (FN), Indirect Tension Cracking Test …
A Software Availability Model Based On Multilevel Software Rejuvenation Andmarkov Chain, Zahra Rahmani Ghobadi, Hassan Rashidi
A Software Availability Model Based On Multilevel Software Rejuvenation Andmarkov Chain, Zahra Rahmani Ghobadi, Hassan Rashidi
Turkish Journal of Electrical Engineering and Computer Sciences
Increasing use of software, rapid and unavoidable changes in the operational environment bring many problemsfor software engineers. One of these problems is the aging and degradation of software performance. Software rejuvenationis a proactive and preventive approach to counteract software aging. Generally, when software is initiated, amounts ofmemory are allocated. Then, the body of software is executed for providing a service and when the software is terminated,the allocated memory is released. In this paper, a rejuvenation model based on multilevel software rejuvenation andMarkov chain presented. In this model, the system performance as a result of degraded physical memory and memoryusage is …
Equivalent Consumption Minimization Strategy With Consideration Of Battery Aging For Parallel Hybrid Electric Vehicles, Bin Zhou, Jeffrey Burl, Amir Rezaei
Equivalent Consumption Minimization Strategy With Consideration Of Battery Aging For Parallel Hybrid Electric Vehicles, Bin Zhou, Jeffrey Burl, Amir Rezaei
Michigan Tech Publications
The equivalent consumption minimization strategy (ECMS) is a well-known energy management strategy for Hybrid Electric Vehicles (HEV). ECMS is very computationally efficient since it yields an instantaneous optimal control. ECMS has been shown to minimize fuel consumption under certain conditions. But, minimizing the fuel consumption often leads to excessive battery damage. This paper introduces a new optimal control problem where the cost function includes terms for both fuel consumption and battery aging. The Ah-throughput method is used to quantify battery aging. ECMS (with the appropriate equivalence factor) is shown to also minimize the cost function that incorporates battery aging. Simulation …
Laboratory Evaluation Of The Residue Of Rubber-Modified Emulsified Asphalt, Dongdong Ge, Xiaodong Zhou, Siyu Chen, Dongzhao Jin, Zhanping You
Laboratory Evaluation Of The Residue Of Rubber-Modified Emulsified Asphalt, Dongdong Ge, Xiaodong Zhou, Siyu Chen, Dongzhao Jin, Zhanping You
Michigan Tech Publications
Emulsified asphalt has been widely used in various surface treatment methods such as chip seal for low-volume road preservation. Using modified emulsified asphalt made it possible to use chip seal technology on medium-and even high-volume traffic pavements. The main objective of the study is to quantify the residue characteristics of rubber-modified emulsified asphalt and to assess the effectiveness of using crumb rubber to modify emulsified asphalt binder. The four emulsified asphalt residues used the distillation procedure. Then, the rheology characteristics of emulsified asphalt residue were evaluated. The Fourier transform infrared spectroscopy (FTIR) test analyzed the chemical change of emulsified asphalt …
Detecting Symptoms Of Chronic Obstructive Pulmonary Disease And Congestive Heart Failure Via Cough And Wheezing Sounds Using Smart-Phones And Machine Learning, Anthony Windmon
USF Tampa Graduate Theses and Dissertations
Chronic Obstructive Pulmonary Disease (COPD) and Congestive Heart Failure (CHF) are progressive disorders, and major health concerns among today’s aging population. COPD causes a large mucus buildup in the lungs, leading to chronic cough and difficulty to breathe. CHF causes fluid buildup in the lower lungs due to the failing heart, causing cough and difficulty to breath. People who are clinically diagnosed with COPD or CHF are expected to regularly monitor their symptoms and follow complex medical recommendations in an effort to prevent exacerbation. In this dissertation, we elaborate upon three different machine learning based techniques that we developed for …
Cardiorespiratory Fitness Diminishes The Effects Of Age On White Matter Hyperintensity Volume, Nathan F. Johnson, Ahmed A. Bahrani, David K. Powell, Gregory A. Jicha, Brian T. Gold
Cardiorespiratory Fitness Diminishes The Effects Of Age On White Matter Hyperintensity Volume, Nathan F. Johnson, Ahmed A. Bahrani, David K. Powell, Gregory A. Jicha, Brian T. Gold
Physical Therapy Faculty Publications
White matter hyperintensities (WMHs) are among the most commonly observed marker of cerebrovascular disease. Age is a key risk factor for WMH development. Cardiorespiratory fitness (CRF) is associated with increased vessel compliance, but it remains unknown if high CRF affects WMH volume. This study explored the effects of CRF on WMH volume in community-dwelling older adults. We further tested the possibility of an interaction between CRF and age on WMH volume. Participants were 76 adults between the ages of 59 and 77 (mean age = 65.36 years, SD = 3.92) who underwent a maximal graded exercise test and structural brain …
Microrna Gene Expression States Underlying Individual Variation In Aging And Lifespan In Isogenic C. Elegans, Holly Kinser
Microrna Gene Expression States Underlying Individual Variation In Aging And Lifespan In Isogenic C. Elegans, Holly Kinser
McKelvey School of Engineering Theses & Dissertations
Average lifespan differs greatly between species, but lifespan among same-species individuals is also highly variable. While much effort has been devoted to uncovering longevity-associated traits and lifespan-extending perturbations in humans and model organisms, how differences in lifespan arise between individuals is unknown. Studies of human identical twins demonstrate that surprisingly little of the variation in lifespan between individuals can be explained by genetics and shared environment. Furthermore, even genetically identical C. elegans reared in highly homogeneous environments display a degree of variability in lifespan similar to that of outbred human populations. Thus, longevity must be determined at least in part …
Brain Structure Changes Over Time In Normal And Mildly Impaired Aged Persons, Charles D. Smith, Linda J. Van Eldik, Gregory A. Jicha, Frederick A. Schmitt, Peter T. Nelson, Erin L. Abner, Richard J. Kryscio, Richard R. Murphy, Anders H. Andersen
Brain Structure Changes Over Time In Normal And Mildly Impaired Aged Persons, Charles D. Smith, Linda J. Van Eldik, Gregory A. Jicha, Frederick A. Schmitt, Peter T. Nelson, Erin L. Abner, Richard J. Kryscio, Richard R. Murphy, Anders H. Andersen
Neurology Faculty Publications
Structural brain changes in aging are known to occur even in the absence of dementia, but the magnitudes and regions involved vary between studies. To further characterize these changes, we analyzed paired MRI images acquired with identical protocols and scanner over a median 5.8-year interval. The normal study group comprised 78 elders (25M 53F, baseline age range 70-78 years) who underwent an annual standardized expert assessment of cognition and health and who maintained normal cognition for the duration of the study. We found a longitudinal grey matter (GM) loss rate of 2.56 ± 0.07 ml/year (0.20 ± 0.04%/year) and a …
A Compendium Of Single Cell Analysis In Aging And Disease, Uday Chintapula, Samir M. Iqbal, Young-Tae Kim
A Compendium Of Single Cell Analysis In Aging And Disease, Uday Chintapula, Samir M. Iqbal, Young-Tae Kim
Electrical and Computer Engineering Faculty Publications and Presentations
Cell is the fundamental structural and functional unit of complex multicellular organisms. Conventional methods which involve average analysis of cells in bulk populations can undermine physiologically significant cell populations, whereas analysis of cells at a single cell level may reveal unique biomarkers and other mechanisms that govern the genotype and phenotype in various physiological processes in presumed homogenous cell populations. Cellular abnormalities such as irregularities in cellular mechanisms have been linked to human aging and other major diseases including neurodegenerative, vascular, autoimmune, and cancer. Aging is a functional decline associated with various diseases in an organism, majorly arising from cellular …
The Laboratory Performance And Aging Characteristics Of Rubber Modified Asphalt Mixture Using A Dry Process, Dongdong Ge
The Laboratory Performance And Aging Characteristics Of Rubber Modified Asphalt Mixture Using A Dry Process, Dongdong Ge
Dissertations, Master's Theses and Master's Reports
The accumulation of waste tires generates severe environmental issues. Using crumb rubber processed from waste tires on the pavement could relieve the pressure of waste tire on the environment and improve the performance of the pavement as well. The application of crumb rubber on the pavement using the dry process was proved to be a cost-effective strategy in some projects, however, the interaction between the rubber and asphalt binder was unknown in the rubber modified asphalt mixture using the dry process, especially when reclaimed asphalt pavement was adopted. The performance improvement of the rubber particle to the asphalt mixture was …
An Efficient Reliability Simulation Tool For Lifetime-Aware Analog Circuit Synthesis, Engi̇n Afacan
An Efficient Reliability Simulation Tool For Lifetime-Aware Analog Circuit Synthesis, Engi̇n Afacan
Turkish Journal of Electrical Engineering and Computer Sciences
Time-dependent degradation (aging) has become more severe in modern CMOS technologies. Therefore, it is highly critical to capture the variation effects and design reliable circuits against aging. Simulation of time-dependent variations is quite complicated since the degradation is a function of time, where the step count of simulation directly affects the accuracy and the efficiency of the analysis. Commercial simulator tools use a constant step count during reliability simulations, in which choosing a large step count degrades the efficiency whereas keeping it small may result in accuracy problems. To overcome this bottleneck, a couple of different approaches have been proposed …
Evaluating Rubber Aging On Tire Durability: Quantitative Evaluation Of Rubber Aging, Brian Auffenberg
Evaluating Rubber Aging On Tire Durability: Quantitative Evaluation Of Rubber Aging, Brian Auffenberg
Williams Honors College, Honors Research Projects
Rubber is considered one of the most important polymers in the world due to its variety of uses. There are many different conditions that can affect the useful life of rubber. The purpose of this research was to determine how the mechanical loading on the rubber may affect the aging of the rubber. The scope of the project was to focus on the rubber used for tire production. The research was limited to focusing only on rubber supplied by industry mentors which was styrene-butadiene rubber. By varying the length of time for testing as well as the temperature of the …
Post-Acquisition Processing Confounds In Brain Volumetric Quantification Of White Matter Hyperintensities, Ahmed A. Bahrani, Omar M. Al-Janabi, Erin L. Abner, Shoshana H. Bardach, Richard J. Kryscio, Donna M. Wilcock, Charles D. Smith, Gregory A. Jicha
Post-Acquisition Processing Confounds In Brain Volumetric Quantification Of White Matter Hyperintensities, Ahmed A. Bahrani, Omar M. Al-Janabi, Erin L. Abner, Shoshana H. Bardach, Richard J. Kryscio, Donna M. Wilcock, Charles D. Smith, Gregory A. Jicha
Neurology Faculty Publications
BACKGROUND: Disparate research sites using identical or near-identical magnetic resonance imaging (MRI) acquisition techniques often produce results that demonstrate significant variability regarding volumetric quantification of white matter hyperintensities (WMH) in the aging population. The sources of such variability have not previously been fully explored.
NEW METHOD: 3D FLAIR sequences from a group of randomly selected aged subjects were analyzed to identify sources-of-variability in post-acquisition processing that can be problematic when comparing WMH volumetric data across disparate sites. The methods developed focused on standardizing post-acquisition protocol processing methods to develop a protocol with less than 0.5% inter-rater variance.
RESULTS: A series …
Investigation Of The Effect Of Age On Regenerative Outcomes Following Treatment Of Volumetric Muscle Loss Injuries, John Taehwan Kim
Investigation Of The Effect Of Age On Regenerative Outcomes Following Treatment Of Volumetric Muscle Loss Injuries, John Taehwan Kim
Graduate Theses and Dissertations
Volumetric muscle loss (VML) is a traumatic injury in skeletal muscle resulting in the bulk loss of more than 20% of the muscle’s volume. Included in the bulk loss of muscle is the skeletal muscle niche comprised of nerve bundles, vasculature, local progenitor cells, basal lamina, and muscle fibers, overwhelming innate repair mechanisms. The hallmark of VML injury is the excessive accumulation of non-contractile, fibrotic tissue and permanent functional deficits. Though predominant in the younger demographic, the elderly population is also captured within VML injuries. There are many factors that change with aging in skeletal muscle that may further hinder …