Engineering Commons^™

Fluid Agitation Studies For Drug Product Containers Using Computational Fluid Dynamics, Matthew Hiroki Ichinose

Master's Theses

At Amgen, the Automated Vision Inspection (AVI) systems capture the movement of unwanted particles in Amgen's drug product containers. For quality inspection, the AVI system must detect these undesired particles using a high speed spin-stop agitation process. To better understand the fluid movements to swirl the particles away from the walls, Computational Fluid Dynamics (CFD) is used to analyze the nature of the two phase flow of air and a liquid solution.

Several 2-D and 3-D models were developed using Fluent to create simulations of Amgen's drug product containers for a 1 mL syringe, 2.25 mL syringe, and a 5 …

A Computational Fluid Dynamics (Cfd) Analysis Of The Aerodynamic Effects Of The Seams On A Two-Dimensional Representation Of A Soccer Ball, Allen R. Rohr

Master's Theses

Most major sports today use a dedicated ball or projectile with specific shape, size, and surface geometry, except for soccer. Over the history of the sport, the surface geometry and design stayed relatively unchanged, sewn together using 32 pentagonal and hexagonal panels. However, recent innovations in panel designs differ substantially from the traditional 32 panel ball. The effects these new designs have on the aerodynamic characteristics of the ball have remained largely unknown, even with the influx of experimental research completed in the past decade. Experimental studies have been broad in scope, analyzing an entire ball in wind tunnels or …