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Washington University in St. Louis

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2018

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Articles 1 - 21 of 21

Full-Text Articles in Engineering

Asme Design Competition - Group H, Melanie Self, Ben Tattersfield, Joshua Emde Oct 2018

Asme Design Competition - Group H, Melanie Self, Ben Tattersfield, Joshua Emde

Mechanical Engineering Design Project Class

This document presents our solution for the ASME pick-and-place design competition. In brief, the challenge is to collect balls from an arena and return them to a ‘home base’. The specifics of the competition are elaborated on within. The document walks through the design decisions that went into the prototype; the Goalkeeper concept that we ultimately landed on best solved the problems presented by the challenge statement as interpreted by our customer, Dr. James Jackson Potter. Several of the design choices were made by applying mathematical relationships, with the math and results included to illuminate our methods. We include a …


Group O - Lacrosse Ball Passer, Mackenzie Gordon, Jake Mennemeier, Conor Pellas Oct 2018

Group O - Lacrosse Ball Passer, Mackenzie Gordon, Jake Mennemeier, Conor Pellas

Mechanical Engineering Design Project Class

The goal of our design group was to make a lacrosse ball passer that could be used in a team practice or individual setting. Wayne Jaekle, WashU’s head lacrosse coach defined major customer needs as producing a consistent pass speed and angle, an interactive interface allowing an automatic time interval between passes, and being easy to load. These needs lead to our main design goals: 1. A ball capacity of 30, 2. A minimum pass speed of 30 mph, and 3. A 5 second time interval between passes. Mock ups and brainstorming exercises led to our team’s selection of a …


T-Shirt Square Cutter, Austin Chawgo, Kendall Weishaar, Samir Lopez Oct 2018

T-Shirt Square Cutter, Austin Chawgo, Kendall Weishaar, Samir Lopez

Mechanical Engineering Design Project Class

Each year, Americans waste millions of pounds of textiles in the form of clothing that is thrown away. Professor Mary Ruppert-Stroescu from the Sam Fox School of Design seeks to combat this by reusing the old fabric from discarded clothes and creating new, fashionable clothing. To do this, her and her students cut up donated shirts into small squares, by hand, using scissors and fabric cutters and sew them together using a method developed by her.. This process is very time consuming and limits the commercial viability of this process. The T-shirt Cutter design, detailed below, has the potential to …


Arliss Competition Canister Vehicle, Jessie Goldberg, Nicholas Cornejo, Tyler Smith, Rachel Kershner Oct 2018

Arliss Competition Canister Vehicle, Jessie Goldberg, Nicholas Cornejo, Tyler Smith, Rachel Kershner

Mechanical Engineering Design Project Class

For our project, we designed a canister vehicle that fits the design specifications of the ARLISS competition. For the ARLISS competition, the vehicles are loaded into a rocket, launched approximately 10,000 feet into the air, released, and then must autonomously navigate to a predetermined target on the ground. Because of our time restraint, we are focused on designing a vehicle of the correct dimensions (a maximum mass of 1050g, a maximum diameter of 146mm, and a maximum height of 240mm) that can simply travel on the ground over multiple types of terrain. Additionally, we designed a parachute release mechanism so …


Universal Tube Fixture, Griffin Kivitz, Matthew Whitehill, Jason Hsu Oct 2018

Universal Tube Fixture, Griffin Kivitz, Matthew Whitehill, Jason Hsu

Mechanical Engineering Design Project Class

The goal of this design project was to create a device that can aid in the assembly of glue joints between concentric tubes. In many medical devices, whether they be laser probes, retractable injectors, or other devices with actuating parts, there are often concentric glue joints. The problem we are trying to solve is controlling where the 2 tubes are relative to one another when they are glued.


Residential Automatic Door Opener, Steven Downs, Ardian Pollo, Ethan Bredemeier Oct 2018

Residential Automatic Door Opener, Steven Downs, Ardian Pollo, Ethan Bredemeier

Mechanical Engineering Design Project Class

This project proposes an innovative design for an automatic door opener intended for external doors of residential homes. The intended customers are elderly and disabled people who may benefit from such a device while entering and exiting their homes. The goal is to create an affordable product to compete with existing products that are relatively expensive to make such devices more accessible.


Anisotropic Tissue Maker, Jake Ireland, Jaryd Huffman, Sarah Mohrmann, Daniel Cano Oct 2018

Anisotropic Tissue Maker, Jake Ireland, Jaryd Huffman, Sarah Mohrmann, Daniel Cano

Mechanical Engineering Design Project Class

Traumatic brain injury (TBI) is a common injury that is not thoroughly understood. Data on brain mechanics and motion are not abundant during the time of impact. In order to accumulate more data and achieve a better understanding of how the injury occurs tissue mimics can be made.


Autonomous Ground Photographer, Sylvia Tan, Nicholas C. Smith, Kate Padilla, Elise Ashley Oct 2018

Autonomous Ground Photographer, Sylvia Tan, Nicholas C. Smith, Kate Padilla, Elise Ashley

Mechanical Engineering Design Project Class

Dr. Penczykowski, a biology professor at Washington University in St. Louis, researches the effects of powdery mildew on three plant species. Her lab currently collects data in the field by manually counting the number of infected plants with the assistance of a simple PVC grid. Therefore, this projects aims to automate this process by capturing images that can then be processed in her lab after.


Group L: T-Shirt2 Cutter, Sophie Anderson, Avery German, Taylor Tuleja Oct 2018

Group L: T-Shirt2 Cutter, Sophie Anderson, Avery German, Taylor Tuleja

Mechanical Engineering Design Project Class

The T-shirt square cutter was commissioned by fashion design professor at Washington University, Dr. Mary RuppertStroescu who has developed a method of turning T-shirts that might have otherwise been thrown away into a unique, woven fabric. Dr. Ruppert-Stroescu cuts T-shirts into either strips or squares that she then quilts together, she uses this fabric to make one-of-a-kind clothes, bags, and rugs. Though she is proficient at weaving the fabric scraps together, cutting the Tshirts was a very time-consuming process – it takes her at least 20 minutes to cut a T-shirt into squares by hand. Our team was tasked with …


Lacrosse Ball Passing Machine, William Galik, Daniel Finer, Matt Jenkins Oct 2018

Lacrosse Ball Passing Machine, William Galik, Daniel Finer, Matt Jenkins

Mechanical Engineering Design Project Class

Design and build a lacrosse ball passing machine that utilizes an automated ball sorting mechanism to shoot balls up to 60 mph with 80 percent accuracy at a 1 square yard target.


Pick And Place Bot: Asme Design Challenge, Steven Mumford, Josh Clark, Stephan Meyer Oct 2018

Pick And Place Bot: Asme Design Challenge, Steven Mumford, Josh Clark, Stephan Meyer

Mechanical Engineering Design Project Class

Design a bot that meets the standards of and is able to compete in the 2019 ASME Design Challenge.


Group T Asme Design Challenge Project, Thomas Orgielewicz, Hayden Von Hoffmann, Michael Chirumbole Oct 2018

Group T Asme Design Challenge Project, Thomas Orgielewicz, Hayden Von Hoffmann, Michael Chirumbole

Mechanical Engineering Design Project Class

Design and build a RC Robot eligible to compete in the 2019 ASME Challenge, the "Pick-and-Place Race"


Tendon Rehabilitator, David Ricks, Lucas Parisot, Benjamin Wang Oct 2018

Tendon Rehabilitator, David Ricks, Lucas Parisot, Benjamin Wang

Mechanical Engineering Design Project Class

Our goal was to provide a cheap, portable and easy way for those suffering from medial epicondylitis tendinosis, or golfers elbow, to perform rehabbing exercises.


Group B: Polar Coordinate Whiteboard Writer, Dylan Wu, Zexin Han, Keon Kim, Jiahao Wei Oct 2018

Group B: Polar Coordinate Whiteboard Writer, Dylan Wu, Zexin Han, Keon Kim, Jiahao Wei

Mechanical Engineering Design Project Class

From the initial funding of $250.00, our group attempted to make a polar coordinate whiteboard writer that was to be used in educational settings. Market for polar coordinate whiteboard writer is a blue ocean. Having a successful prototype will allow us to find a niche place in a market that shares border with the global education market.


Group V: Color Mixer, Kate Baskin, Mark Livshin, Andy Johnston Oct 2018

Group V: Color Mixer, Kate Baskin, Mark Livshin, Andy Johnston

Mechanical Engineering Design Project Class

This project was an exercise in product design, modeling, and prototyping. The result of this process was a partially functional prototype which successfully met two of the three design goals.


Decoupling Information And Connectivity Via Information-Centric Transport, Hila Ben Abraham, Jyoti Parwatikar, John Dehart, Adam Drescher, Patrick Crowley Aug 2018

Decoupling Information And Connectivity Via Information-Centric Transport, Hila Ben Abraham, Jyoti Parwatikar, John Dehart, Adam Drescher, Patrick Crowley

Computer Science and Engineering Publications and Presentations

The power of Information-Centric Networking (ICN) architectures lies in their abstraction for communication --- the request for named data. This abstraction promises that applications can choose to operate only in the information plane, agnostic to the mechanisms implemented in the connectivity plane. However, despite this powerful promise, the information and connectivity planes are presently coupled in today's incarnations of leading ICNs by a core architectural component, the forwarding strategy. Presently, this component is not sustainable: it implements both the information and connectivity mechanisms without specifying who should choose a forwarding strategy --- an application developer or the network operator. In …


Security Services Using Blockchains: A State Of The Art Survey, Maeda Zolanvari, Aiman Erbad, Raj Jain, Mohammed Samaka Aug 2018

Security Services Using Blockchains: A State Of The Art Survey, Maeda Zolanvari, Aiman Erbad, Raj Jain, Mohammed Samaka

All Computer Science and Engineering Research

This article surveys blockchain-based approaches for several security services. These services include authentication, confidentiality, privacy and access control list (ACL), data and resource provenance, and integrity assurance. All these services are critical for the current distributed applications, especially due to the large amount of data being processed over the networks and the use of cloud computing. Authentication ensures that the user is who he/she claims to be. Confidentiality guarantees that data cannot be read by unauthorized users. Privacy provides the users the ability to control who can access their data. Provenance allows an efficient tracking of the data and resources …


Super‐Resolution Imaging Of Amyloid Structures Over Extended Times By Using Transient Binding Of Single Thioflavin T Molecules, Kevin Spehar, Tianben Ding, Yuanzi Sun, Niraja Kedia, Jin Lu, George R. Nahass, Matthew D. Lew, Jan Bieschke Jun 2018

Super‐Resolution Imaging Of Amyloid Structures Over Extended Times By Using Transient Binding Of Single Thioflavin T Molecules, Kevin Spehar, Tianben Ding, Yuanzi Sun, Niraja Kedia, Jin Lu, George R. Nahass, Matthew D. Lew, Jan Bieschke

Electrical & Systems Engineering Publications and Presentations

Oligomeric amyloid structures are crucial therapeutic targets in Alzheimer's and other amyloid diseases. However, these oligomers are too small to be resolved by standard light microscopy. We have developed a simple and versatile tool to image amyloid structures by using thioflavin T without the need for covalent labeling or immunostaining. The dynamic binding of single dye molecules generates photon bursts that are used for fluorophore localization on a nanometer scale. Thus, photobleaching cannot degrade image quality, allowing for extended observation times. Super‐resolution transient amyloid binding microscopy promises to directly image native amyloid by using standard probes and record amyloid dynamics …


Imaging The Three-Dimensional Orientation And Rotational Mobility Of Fluorescent Emitters Using The Tri-Spot Point Spread Function, Oumeng Zhang, Jin Lu, Tianben Ding, Matthew D. Lew Jun 2018

Imaging The Three-Dimensional Orientation And Rotational Mobility Of Fluorescent Emitters Using The Tri-Spot Point Spread Function, Oumeng Zhang, Jin Lu, Tianben Ding, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

Fluorescence photons emitted by single molecules contain rich information regarding their rotational motions, but adapting single-molecule localization microscopy (SMLM) to measure their orientations and rotational mobilities with high precision remains a challenge. Inspired by dipole radiation patterns, we design and implement a Tri-spot point spread function (PSF) that simultaneously measures the three-dimensional orientation and the rotational mobility of dipole-like emitters across a large field of view. We show that the orientation measurements done using the Tri-spot PSF are sufficiently accurate to correct the anisotropy-based localization bias, from 30 nm to 7 nm, in SMLM. We further characterize the emission anisotropy …


A Robust Statistical Estimation (Rose) Algorithm Jointly Recovers The 3d Location And Intensity Of Single Molecules Accurately And Precisely, Hesam Mazidi, Arye Nehorai, Matthew D. Lew Feb 2018

A Robust Statistical Estimation (Rose) Algorithm Jointly Recovers The 3d Location And Intensity Of Single Molecules Accurately And Precisely, Hesam Mazidi, Arye Nehorai, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

In single-molecule (SM) super-resolution microscopy, the complexity of a biological structure, high molecular density, and a low signal-to-background ratio (SBR) may lead to imaging artifacts without a robust localization algorithm. Moreover, engineered point spread functions (PSFs) for 3D imaging pose difficulties due to their intricate features. We develop a Robust Statistical Estimation algorithm, called RoSE, that enables joint estimation of the 3D location and photon counts of SMs accurately and precisely using various PSFs under conditions of high molecular density and low SBR.


Measuring 3d Molecular Orientation And Rotational Mobility Using A Tri-Spot Point Spread Function, Oumeng Zhang, Tianben Ding, Jin Lu, Hesam Mazidi, Matthew D. Lew Feb 2018

Measuring 3d Molecular Orientation And Rotational Mobility Using A Tri-Spot Point Spread Function, Oumeng Zhang, Tianben Ding, Jin Lu, Hesam Mazidi, Matthew D. Lew

Electrical & Systems Engineering Publications and Presentations

We present a method to measure the molecular orientation and rotational mobility of single-molecule emitters by designing and implementing a Tri-spot point spread function. It can measure all degrees of freedom related to molecular orientation and rotational mobility. Its design is optimized by maximizing the theoretical limit of its measurement precision. We evaluate the precision and accuracy of the Tri-spot PSF by measuring the orientation and effective rotational mobility of single fluorescent molecules embedded in a polymer matrix.