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Full-Text Articles in Engineering
Predicting Neointimal Hyperplasia In Stented Arteries Using Time-Dependant Computational Fluid Dynamics: A Review, Jonathan Murphy, Fergal Boyle
Predicting Neointimal Hyperplasia In Stented Arteries Using Time-Dependant Computational Fluid Dynamics: A Review, Jonathan Murphy, Fergal Boyle
Articles
This paper reviews the recent literature regarding the time-dependant computational fluid dynamics (CFD) analyses of blood flow through implanted coronary stents. The in vivo processes which result in arterial restenosis are identified. The definition and range of the computationally predicted variables which are believed to stimulate the restenosis processes are evaluated. The reviewed literature is subdivided into effect-based in which the effects of altering the flow model are investigated and design-based in which different geometric stent configurations are compared. Finally, conclusions are made regarding the body of work reviewed and recommendations are provided for future work in this field.
A Multi-Variable Analysis Of Transient Near-Wall Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle
A Multi-Variable Analysis Of Transient Near-Wall Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle
Conference Papers
No abstract provided.
Development Of A Three Dimensional Prolapse Model To Simulate Physiological Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle
Development Of A Three Dimensional Prolapse Model To Simulate Physiological Haemodynamics In A Stented Coronary Artery, Jonathan Murphy, Fergal Boyle
Conference Papers
Coronary stent implantation can improve blood flow in an artery that has been narrowed by the build up of arterial plaque. However, the haemodynamic effect of stent placement is unclear and may influence arterial restenosis (re-blockage). The degree of tissue prolapse between stent struts may be an important factor in predicting the restenosis rate of a stent due to the haemodynamic influence of the protruding tissue. In this paper a mathematical model has been developed to numerically predict the tissue prolapse for an artery implanted with a coronary stent. The prolapse model has been applied to the Gianturco-Roubin II (GR-II) …
Evolution Of A Computational Domain For Numerical Analysis Of Fluid Mechanical Disturbance Induced By Coronary Stent Deployment, Jonathan Murphy, Fergal Boyle
Evolution Of A Computational Domain For Numerical Analysis Of Fluid Mechanical Disturbance Induced By Coronary Stent Deployment, Jonathan Murphy, Fergal Boyle
Conference Papers
No abstract provided.
Application Of Advanced Computational Modelling In The Numerical Prediction Of The Haemodynamic Impact Of Coronary Stent Implantation, Jonathan Murphy, Fergal Boyle
Application Of Advanced Computational Modelling In The Numerical Prediction Of The Haemodynamic Impact Of Coronary Stent Implantation, Jonathan Murphy, Fergal Boyle
Conference Papers
Coronary stent implantation can improve blood flow in an artery narrowed by the build up of arterial plaque. However, the haemodynamic effect of stent placement is unclear and may influence arterial restenosis (re-blockage). In this investigation the stent induced, non-Newtonian blood flow disturbances have been captured in a three dimensional computational domain. The results clearly show areas of low wall shear stress proximal and distal to the stent wires, a characteristic which is known to encourage restenosis. Furthermore, this computational method of observing the complex haemodynamics of the stent environment can be used in conjunction with medical trial data to …