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Numerical Modelling Of Red Blood Cell Structural Mechanics, Mingzhu Chen

Doctoral

Red blood cells (RBCs) are the most abundant cellular elements in blood and their main function is the oxygen delivery. Structurally RBCs are highly deformable membrane-bounded liquid-core capsules. The deformability is critical to fulfill the functionality and is greatly affected by the RBC structural mechanics. Due to the small size, in vivo/vitro studies of the RBCs are often impossible where, being an alternative, numerical modellings stand out to be a robust approach to investigate the the RBC. In the recent years the spring-particle-based (SP) RBC modelling becomes very popular due to the simplicity and extensive modelling capability over the conventional …