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Using Optimization To Calibrate Models Of Intracranial Pressure Dynamics To Patients With Intracranial Hypertension, Wayne W. Wakeland, A. Bulbul, Mateo Aboy, James Mcnames, Brahm Goldstein
Using Optimization To Calibrate Models Of Intracranial Pressure Dynamics To Patients With Intracranial Hypertension, Wayne W. Wakeland, A. Bulbul, Mateo Aboy, James Mcnames, Brahm Goldstein
Systems Science Faculty Publications and Presentations
Aim: Automatically calibrate ICP Dynamic model to a specific patients.
Method: Use optimization algorithm to estimate parameter values (ICP, compliances, resistances) that minimize the squared error in predicted ICP.
Results: Estimated parameter values are plausible and improve predicted ICP. Optimization time for 18 minute episode = 2.5 min. for 1 parameter, 10 to 200 min. for multiple simultaneous parameters (too long).