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Full-Text Articles in Engineering

Thermodynamically-Constrained Computational Modeling Of Lung Tissue Bioenergetics And The Effect Of Hyperoxia-Induced Acute Lung Injury, Xiao Zhang Apr 2019

Thermodynamically-Constrained Computational Modeling Of Lung Tissue Bioenergetics And The Effect Of Hyperoxia-Induced Acute Lung Injury, Xiao Zhang

Dissertations (1934 -)

Altered lung tissue bioenergetics is an important and early step in the pathogenesis of acute lung injury (ALI), one of the most common causes of admission to medical ICUs. A wealth of information exists regarding the effect of ALI on specific mitochondrial and cytosolic processes in isolated mitochondria, cultured endothelial cell, and intact lungs. However, the interdependence of lung cellular processes makes it difficult to quantify the impact of a change in a single or multiple cellular process(es) on overall lung tissue bioenergetics. Integrating bioenergetics data from isolated mitochondria and intact lung is necessary for determining the functional significance of …


Computationally Efficient Strand Eddy Current Loss Calculation In Electric Machines, Alireza Fatemi, Dan M. Ionel, Nabeel Demerdash, Dave A. Staton, Rafal Wrobel, Yew Chuan Chong Mar 2019

Computationally Efficient Strand Eddy Current Loss Calculation In Electric Machines, Alireza Fatemi, Dan M. Ionel, Nabeel Demerdash, Dave A. Staton, Rafal Wrobel, Yew Chuan Chong

Electrical and Computer Engineering Faculty Research and Publications

A fast finite element (FE) based method for the calculation of eddy current losses in the stator windings of randomly wound electric machines is presented in this paper. The method is particularly suitable for implementation in large-scale design optimization algorithms where a qualitative characterization of such losses at higher speeds is most beneficial for identification of the design solutions that exhibit the lowest overall losses including the ac losses in the stator windings. Unlike the common practice of assuming a constant slot fill factor s f for all the design variations, the maximum s f in the developed method is …