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Engineering Conferences International

Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications

2015

Antioxidant

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Full-Text Articles in Engineering

What's In The Bag?, Rebecca Olsen, Diane Hahm, Jing Li Oct 2015

What's In The Bag?, Rebecca Olsen, Diane Hahm, Jing Li

Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications

As the bioprocessing industry continues to shift towards single-use systems, there is an increasing need for polymers with improved functionality. This article includes a review of the chemistry and functionality of various polymeric families, and a description of various tools that can be useful. Polyethylene resins are largely used in a variety of single use applications. This paper describes polyethylene chemistry in more detail so that single use system manufacturers and biopharmaceuticals manufacturers can optimize the use of polyethylene polymers in a particular application. The process in which the families of polyethylene polymer resins are manufactured dictates the degree of …


Polyolefins And Their Influence On Single Use Technology For Bioprocessing, Amy Plancon, Marnik Vaes Oct 2015

Polyolefins And Their Influence On Single Use Technology For Bioprocessing, Amy Plancon, Marnik Vaes

Single-Use Technologies: Bridging Polymer Science to Biotechnology Applications

The presentation will focus on polyolefins and their use in single use systems for bioprocessing and the manufacture of biologic drugs. The nature of polyethylene and polypropylene will be explored, as well as material properties and how those properties can be influenced by the polymer manufacturer to meet specific needs in the market. This influence might include the introduction of additives, the substitution of specific ingredients, and the promotion/development of particular processing conditions. The impact of antioxidants will be presented, along with an overview of extractables and leachables protocol as they relate to the polyolefin family.