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Michael L.F. Lerch

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Microbeam Radiation Therapy: A Monte Carlo Study Of The Influence Of The Source, Multislit Collimator, And Beam Divergence On Microbeams, Heidi Nettelbeck, George Takacs, Michael Lerch, Anatoly Rosenfeld Nov 2013

Microbeam Radiation Therapy: A Monte Carlo Study Of The Influence Of The Source, Multislit Collimator, And Beam Divergence On Microbeams, Heidi Nettelbeck, George Takacs, Michael Lerch, Anatoly Rosenfeld

Michael L.F. Lerch

Microbeam radiation therapy (MRT) is a new oncology method currently under development for the treatment of inoperable pediatric brain tumors. Monte Carlo simulation, or the computational study of radiation transport in matter, is often used in radiotherapy to theoretically estimate the dose required for treatment. However, its potential use in MRT dose planning systems is currently hindered by the significant discrepancies that have been observed between measured and theoretical dose and the PVDR (peak to valley dose ratio). The need to resolve these discrepancies is driven by the desirability of making MRT available to humans in the next few years. …