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Full-Text Articles in Engineering
A Label-Free High Throughput Resistive-Pulse Sensor For Simultaneous Differentiation And Measurement Of Multiple Particle-Laden Analytes, Ashish Jagtiani, Rupesh Sawant, Jiang Zhe
A Label-Free High Throughput Resistive-Pulse Sensor For Simultaneous Differentiation And Measurement Of Multiple Particle-Laden Analytes, Ashish Jagtiani, Rupesh Sawant, Jiang Zhe
Dr. Jiang Zhe
We describe an all-electronic, label-free, resistive-pulse sensor that utilizes multiple microchannels for parallel detection, counting and differentiation of multiple biological particles simultaneously. Four particle solutions, including 20 µm and 40 µm polymethacrylate particles, Juniper Scopulorum (Rocky Mountain Juniper) pollen and Populus deltidoes (Eastern Cottonwood) pollen, were loaded to the four peripheral reservoirs, respectively, and were driven to the central reservoir through four microchannels, all operating simultaneously for particle detection and counting. Experiments demonstrated that this sensor was able to differentiate and count multiple particle solutions simultaneously through its four microchannels fabricated on polymer membranes. Thus the sensing throughput has been …
Zwitteration Of Dextran: A Facile Route To Integrate Antifouling, Switchability And Optical Transparency Into Natural Polymers, Bin Cao, Linlin Li, Haiyan Wu, Qiong Tang, Bingbing Sun, He Dong, Jiang Zhe, Gang Cheng
Zwitteration Of Dextran: A Facile Route To Integrate Antifouling, Switchability And Optical Transparency Into Natural Polymers, Bin Cao, Linlin Li, Haiyan Wu, Qiong Tang, Bingbing Sun, He Dong, Jiang Zhe, Gang Cheng
Dr. Jiang Zhe
This communication reports a facile method for zwitteration of dextran with carboxybetaine (CB), which integrates superior antifouling properties, switchability between zwitterionic and cationic forms, as well as enhanced optical transparency into one polysaccharide material. This study provides a new avenue for generating multifunctional zwitterionic CB materials in situ.
Label-Free Biomarker Assay In A Microresistive Pulse Sensor Via Immunoaggregation, Yu Han, Haiyan Wu, Fan Li, Gang Cheng, Jiang Zhe
Label-Free Biomarker Assay In A Microresistive Pulse Sensor Via Immunoaggregation, Yu Han, Haiyan Wu, Fan Li, Gang Cheng, Jiang Zhe
Dr. Jiang Zhe
We present a label-free biomarker detection method based on immunoaggregation and resistive pulse sensing technology. In this approach, target biomarkers and antibody (Ab)-functionalized microparticles are mixed to form biomarker–microparticle aggregates. A resistive pulse sensor is then used to measure the sizes and count the number of aggregates. The measured volume fraction of the aggregates represents the concentration of the targeted biomarker. In our tests, human ferritin, used as a biomarker, triggered the aggregation of antiferritin Ab-functionalized microparticles in phosphate-buffered saline (PBS). The volume fraction of aggregates increased with the increased ferritin concentration. We also demonstrated the detection of human ferritin …
A Multi-Physics Model For Solid Oxide Iron-Air Redox Flow Battery: Simulation Of Discharge Behavior At High Current Density, Meng Guo, Xuan Zhao, Ralph White, Kevin Huang
A Multi-Physics Model For Solid Oxide Iron-Air Redox Flow Battery: Simulation Of Discharge Behavior At High Current Density, Meng Guo, Xuan Zhao, Ralph White, Kevin Huang
Kevin Huang
A rigorous physics-based mathematical model for a solid oxide iron-air redox flow battery system is presented in this paper. The modeled flow battery system combines a Fe-FeO redox couple as the energy storage unit and a regenerative solid oxide fuel cell as the electrical functioning unit in a 2D axial symmetric geometry. This model was developed from fundamental theories of reaction engineering in which basic transport phenomena and chemical/electrochemical kinetics are included. The model shows good agreement with the experimental data. Simulation results for the chemical, electrochemical and transport behavior of the battery are discussed.
In Situ Stress Measurement During Aluminum Anodizing Using Phase-Shifting Curvature Interferometry, Ömer Çapraz, Kurt Hebert, Pranav Shrotriya
In Situ Stress Measurement During Aluminum Anodizing Using Phase-Shifting Curvature Interferometry, Ömer Çapraz, Kurt Hebert, Pranav Shrotriya
Ömer Özgür Çapraz
Stress measurements yield insight into technologically relevant deformation and failure mechanisms in electrodeposition, battery reactions, corrosion and anodic oxidation. Aluminum anodizing experiments were performed to demonstrate the effectiveness of phase-shifting curvature interferometry as a new technique for high-resolution in situ stress measurement. This method uses interferometry to monitor surface curvature changes, from which stress evolution is inferred. Phase-shifting of the reflected beams enhanced measurement sensitivity, and the separation of the optical path from the electrochemical cell in the present system provided increased stability. Curvature changes as small as 10−3 km−1 were detected, at least comparable to the resolution of state-of-the-art …