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Faculty of Engineering and Information Sciences - Papers: Part B

Principles

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Full-Text Articles in Engineering

Structural Principles Analysis Of Host-Pathogen Protein-Protein Interactions: A Structural Bioinformatics Survey, Huaming Chen, William Guo, Jun Shen, Lei Wang, Jiangning Song Jan 2018

Structural Principles Analysis Of Host-Pathogen Protein-Protein Interactions: A Structural Bioinformatics Survey, Huaming Chen, William Guo, Jun Shen, Lei Wang, Jiangning Song

Faculty of Engineering and Information Sciences - Papers: Part B

No abstract provided.


Towards Elucidating The Structural Principles Of Host-Pathogen Protein-Protein Interaction Networks: A Bioinformatics Survey, Huaming Chen, Jiangning Song, Geng Sun, Jun Shen, Lei Wang Jan 2017

Towards Elucidating The Structural Principles Of Host-Pathogen Protein-Protein Interaction Networks: A Bioinformatics Survey, Huaming Chen, Jiangning Song, Geng Sun, Jun Shen, Lei Wang

Faculty of Engineering and Information Sciences - Papers: Part B

The ultimate goal of systems biology research area is to accurately predict the behavior of biological systems through the construction of computational models, using the related molecular-level data as the input, especially when the structural information of such biological system is available. Combining the three-dimensional (3D) structural information of the cohort of macromolecules underpinning the biological system, the researchers are poised with an unprecedented opportunity to gain a full understanding on how the molecules interact with each other, particularly for an interaction network, e.g. protein-protein interaction networks. Specifically, there are currently a limited number of studies focused on the reconstruction …