Engineering Commons^™

Using Fnirs As An Objective Measure Of Susceptibility To Informational Masking, Min Zhang

Dissertations

Resolving complicated auditory scenes is crucial for daily communication where background sound is often present. However, most hearing aid (HA) and cochlear implant (CI) users have difficulties understanding speech when competing sound sources are present, resulting in reduced job opportunities and increased risk for social isolation. Perceptual interference from background sound is called auditory masking. At least two distinct masking phenomena exist, called energetic and informational masking (EM and IM).

In the first masking phenomenon, EM, target and masker energies coincide at the same time and frequency. Computational and physiological models of cochlear auditory processing can reliably predict listeners' performances …

Comparison Of Longitudinal Changes In Resting State Functional Magnetic Resonance Imaging Between Alzheimer’S And Healthy Controls, Berk Can Yilmaz

Theses

Resting State Functional Magnetic Resonance Imaging (rs-fMRI) is a technique that is widely used for analyzing brain function using different approaches and methods. This study involves rs-fMRI analysis of Blood Oxygenation Level Dependent (BOLD) signals acquired from Alzheimer’s disease (AD) Patients and Healthy Controls (HC). Each subject in the study had both functional and anatomical images with at least one rs-fMRI scan with their Anatomical (T1) scans. Previous rs-fMRI studies have demonstrated that AD shows differences in Amplitude of Low Frequency (<0.1 Hz) Fluctuations (ALFF), and Regional Homogeneity (ReHo) measures according to HCs.

The aim of the study is to investigate individual and group level differences using ReHo and mALFF related …

Neurobiological Markers For Remission And Persistence Of Childhood Attention-Deficit/Hyperactivity Disorder, Yuyang Luo

Dissertations

Attention-deficit/hyperactivity disorder (ADHD) is one of the most prevalent neurodevelopmental disorders in children. Symptoms of childhood ADHD persist into adulthood in around 65% of patients, which elevates the risk for a number of adverse outcomes, resulting in substantial individual and societal burden. A neurodevelopmental double dissociation model is proposed based on existing studies in which the early onset of childhood ADHD is suggested to associate with dysfunctional subcortical structures that remain static throughout the lifetime; while diminution of symptoms over development could link to optimal development of prefrontal cortex. Current existing studies only assess basic measures including regional brain activation …