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Articles 1 - 14 of 14
Full-Text Articles in Engineering
Metric Learning Via Linear Embeddings For Human Motion Recognition, Byoungdoo Kong
Metric Learning Via Linear Embeddings For Human Motion Recognition, Byoungdoo Kong
Masters Theses
We consider the application of Few-Shot Learning (FSL) and dimensionality reduction to the problem of human motion recognition (HMR). The structure of human motion has unique characteristics such as its dynamic and high-dimensional nature. Recent research on human motion recognition uses deep neural networks with multiple layers. Most importantly, large datasets will need to be collected to use such networks to analyze human motion. This process is both time-consuming and expensive since a large motion capture database must be collected and labeled. Despite significant progress having been made in human motion recognition, state-of-the-art algorithms still misclassify actions because of characteristics …
Engineering Stimuli-Responsive Polymeric Nanoassemblies: Rational Designs For Intracellular Delivery Of Biologics, Kingshuk Dutta
Engineering Stimuli-Responsive Polymeric Nanoassemblies: Rational Designs For Intracellular Delivery Of Biologics, Kingshuk Dutta
Doctoral Dissertations
Biologic drugs have gained enormous research attention in recent years as reflected by the development of multiple candidates to the clinical pipelines and an increased percentage of FDA approval. This is reasoned by the fact that biologics have been proven to deliver more predictive and promising benefits for many hard-to-cure diseases by ‘drugging the undruggable’ targets. However, the challenges associated with biologic drug development are multi-fold, viz, poor encapsulation efficacy, systemic instability, low cellular internalization and endosomal escape capability. Thus, it is essential to develop new molecular strategies that can not only address the associated drug delivery challenges, but also …
Experimental Study Of Viscoelastic Fluid-Structure Interactions, Anita Anup Dey
Experimental Study Of Viscoelastic Fluid-Structure Interactions, Anita Anup Dey
Doctoral Dissertations
It is well known that when a flexible or flexibly-mounted structure is placed perpendicular to a Newtonian fluid flow, it can oscillate due to the shedding of vortices at high Reynolds numbers. Unlike Newtonian fluids, viscoelastic fluid flow can become unstable even at infinitesimal Reynolds numbers due to a purely elastic flow instability occurring at large Weissenberg numbers. This thesis focuses on exploring the mechanisms of viscoelastic fluid-structure interactions (VFSI) through experimental investigations on several different combinations of flexible and flexibly-mounted circular cylinders, micro and macro-scale cantilevered beams and viscoelastic fluids such as wormlike micelle solutions and polymer solutions. VFSI …
Theory And Improved Methods For Probing The Cavitation To Fracture Transition, Christopher Barney
Theory And Improved Methods For Probing The Cavitation To Fracture Transition, Christopher Barney
Doctoral Dissertations
A material is considered soft when its bulk modulus is significantly greater than its shear modulus. Rubbery polymers are a class of soft materials where resistance to extension is mainly entropic in nature. Polymeric soft solids differ from liquids due to the presence of a percolated network of strong bonds that resist deformation and flow on a given time scale. The incompressible nature, entropically driven elasticity, and molecular scale network structure of soft polymeric solids combine to impart unique mechanical behavior that often results in complex material responses to simple loading situations. An important example of this is cavitation in …
Controlled Membrane Remodeling By Nanospheres And Nanorods: Experiments Targeting The Design Principles For Membrane-Based Materials, Sarah Zuraw-Weston
Controlled Membrane Remodeling By Nanospheres And Nanorods: Experiments Targeting The Design Principles For Membrane-Based Materials, Sarah Zuraw-Weston
Doctoral Dissertations
In this thesis we explore two experimental systems probing the interactions of nanoparticles with lipid bilayer membranes. Inspired by the ability of cell membranes to alter their shape in response to bound particles, we report two experimental studies: one of nanospheres the other of long, slender nano-rods binding to lipid bilayer vesicles and altering the membrane shape. Our work illuminates the role of particle geometry, particle concentration, adhesion strength and membrane tension in how membrane morphology is determined. We combine giant unilamellar vesicles with oppositely charged nanoparticles, carefully tuning adhesion strength, membrane tension and particle concentration. In the case of …
Nano- And Micro-Structured Temperature-Sensitive Hydrogels For Rapidly Responsive Devices, Qi Lu
Nano- And Micro-Structured Temperature-Sensitive Hydrogels For Rapidly Responsive Devices, Qi Lu
Doctoral Dissertations
This thesis aims to extend the understanding and explore the application of temperature-responsive hydrogel systems by integrating microelectromechanical systems (MEMS). Stimuli-responsive hydrogel systems are immensely investigated and applied in numerous fields, and interfacing with micro- and nano-fabrication techniques will open up more possibilities. In Chapter 2, the first biologically relevant, in vitro cell stretching device based on hydrogel surface instability was developed. This dynamic platform is constructed by embedding micro-heater devices under temperature-responsive surface-attached hydrogels. The fast and regional temperature change actuates the stretching and relaxation of the seeded human artery smooth muscle cell (HASMC) via controllable surface creasing instability. …
Design And Implementation Of Path Finding And Verification In The Internet, Hao Cai
Design And Implementation Of Path Finding And Verification In The Internet, Hao Cai
Doctoral Dissertations
In the Internet, network traffic between endpoints typically follows one path that is determined by the control plane. Endpoints have little control over the choice of which path their network traffic takes and little ability to verify if the traffic indeed follows a specific path. With the emergence of software-defined networking (SDN), more control over connections can be exercised, and thus the opportunity for novel solutions exists. However, there remain concerns about the attack surface exposed by fine-grained control, which may allow attackers to inject and redirect traffic. To address these opportunities and concerns, we consider two specific challenges: (1) …
Kinetics Of The Crystal-Melt Phase Transformation In Semicrystalline Polymers, Kiran Subramaniam Iyer
Kinetics Of The Crystal-Melt Phase Transformation In Semicrystalline Polymers, Kiran Subramaniam Iyer
Doctoral Dissertations
The assembly of long-chain polymers into an ordered state is a process that has puzzled polymer scientists for several decades. A process that is largely controlled by the strength of intermolecular attractions in small molecular systems, this crystallization in the case of polymers is controlled by a competition between the aforementioned force of attraction between monomers and the formidable conformational entropy of polymer chains. Any factor that affects this conformational entropy, whether that is an equilibrium thermodynamic factor or a kinetic factor, has the ability to control polymer crystallization. In this thesis, we focus on understanding the underlying kinetic processes …
Compound Effects Of Clock And Voltage Based Power Side-Channel Countermeasures, Jacqueline Lagasse
Compound Effects Of Clock And Voltage Based Power Side-Channel Countermeasures, Jacqueline Lagasse
Masters Theses
The power side-channel attack, which allows an attacker to derive secret information from power traces, continues to be a major vulnerability in many critical systems. Numerous countermeasures have been proposed since its discovery as a serious vulnerability, including both hardware and software implementations. Each countermeasure has its own drawback, with some of the highly effective countermeasures incurring large overhead in area and power. In addition, many countermeasures are quite invasive to the design process, requiring modification of the design and therefore additional validation and testing to ensure its accuracy. Less invasive countermeasures that do not require directly modifying the system …
Metabolic Modeling Of Multispecies Microbial Biofilms, Poonam Phalak
Metabolic Modeling Of Multispecies Microbial Biofilms, Poonam Phalak
Doctoral Dissertations
Biofilms are ubiquitous in medical, environmental, and engineered microbial systems. The majority of naturally occurring microbes grow as mixed species biofilms. These complicated biofilm consortia are comprised of many cell phenotypes with complex interactions and self-organized into three-dimensional structures. Approximately 2% of the US population suffers from non-healing chronic wounds infected by a combination of commensal and pathogenic bacteria whereas about 500,000 cases of Clostridium difficile infections (CDI) are reported annually. These polymicrobial infections are often resilient to antibiotic treatment due to the nutrient-rich environments and species interactions that promote community stability and robustness. This thesis focusses on developing metabolic …
Nanoindentation Characterization Of Elastic Properties Of Shales And Swelling Clay Minerals, Shengmin Luo
Nanoindentation Characterization Of Elastic Properties Of Shales And Swelling Clay Minerals, Shengmin Luo
Doctoral Dissertations
Oil and gas shales are a class of multiscale, multiphase, hybrid inorganic-organic sedimentary rocks that consist of a generally uniform, preferentially oriented clay matrix with randomly embedded silt and sand particles as solid inclusions. A thorough understanding of the mechanical properties of shales is crucial for the exploration and production of oil and gas in the unconventional shale reservoirs, but it can be a challenging task due to their nature of compositional heterogeneity and microstructural anisotropy. In efforts to better characterize the mechanical properties of shales across different length scales and to fundamentally understand the laws of upscaling from individual …
Molecular Design Of Organic Semiconductors For Interfacial And Emissive Material Applications, Marcus David Cole
Molecular Design Of Organic Semiconductors For Interfacial And Emissive Material Applications, Marcus David Cole
Doctoral Dissertations
This dissertation describes the synthesis and characterization of functional optoelectronically active materials. Synthetic techniques were used to prepare polymers containing perylene diimide (PDI) or tetraphenylethylene (TPE) moieties in the polymer backbone. PDI-based structures were prepared with embedded cationic or zwitterionic moieties intended to tailor organic/inorganic interfaces in thin film photovoltaic devices. The aggregation-induced emission (AIE)-active TPE polymers were synthesized to study how AIE properties evolve in π-conjugated polymers. The syntheses discussed here focused on modulation of molecular architecture to give rise to materials with tailored optoelectronic properties. Chapter 1 provides a brief overview of the field of organic electronics and …
Hudson River Estuary Tidal Marsh Sediment Data, Brian Yellen, Jonathan Woodruff
Hudson River Estuary Tidal Marsh Sediment Data, Brian Yellen, Jonathan Woodruff
Data and Datasets
This repository contains data from sediment cores collected at six tidal wetland complexes that are located within the Hudson River Estuary. The sites include Stockport Marsh, Esopus Delta, Tivoli North Bay, Tivoli South Bay, Vanderburgh Cove, and Iona Island Marsh. A variety of core collection tools and methods were used to collect uncompacted records, including gouge coring, Russian peat coring, and piston push coring, with the method determined by coring environment. The general workflow for cores included (1) splitting; (2) Itrax XRF scanning; (3) subsampling cores ~10 cm spacing; (4) drying and burning samples for percent water, organic, and mineral …
Dam Impoundments Sediment Mass – Tributaries To The Hudson River, Brian Yellen, Jonathan Woodruff
Dam Impoundments Sediment Mass – Tributaries To The Hudson River, Brian Yellen, Jonathan Woodruff
Data and Datasets
This repository contains data from sediment cores collected during 2017-2018 from 17 impoundments that are located on tributaries to the tidal portion of the Hudson River as part of a larger NERRs collaborative project entitled Dams and Sediment on the Hudson (DaSH). A companion dataset that contains sediment core data from Hudson tidal marshes is archived at UMass Scholarworks data repository. Sediment cores collected from impoundments behind dams were recovered via piston push coring, which tends to minimize compaction and be representative of true sediment thicknesses. The general workflow for cores included (1) splitting; (2) Itrax XRF scanning; (3) subsampling …