Engineering Commons^™

Relationships Between In-Situ Tests And Soil Cyclic Strength For Earthquake Hazard Characterization In The Pacific Northwest, Tanner Scott Bryantt

Dissertations and Theses

Strong earthquake shaking is a natural hazard threat in the Pacific Northwest. Soil failure due to strong earthquake shaking -- known as cyclic soil failure or liquefaction -- is expected to cause large ground deformations and damage to roads, bridges, and other civil infrastructure. Cyclic soil strength (CRR) is often characterized with in-situ geotechnical tests including the cone penetration test (CPT). Relationships between CRR and in-situ test data are not well established for soils in the Pacific Northwest. Portland State University, in partnership with New Albion Geotechnical has compiled a database of cyclic lab tests for Pacific Northwest soils to …

Indoor Air Quality Impacts Of A Woodstove Exchange Program In Washington County, Oregon, Matthew Forrest Survilo

Dissertations and Theses

More than six million people in the United States use wood stoves as their primary heat source. Wood stoves emit air pollutants that may impact health, e.g., wood combustion products are associated with premature death and aggravation of pulmonary and cardiovascular conditions. There are few studies investigating the efficacy of wood stove exchange programs (WSEPs) as a method to improve indoor air quality (IAQ). In partnership with Washington County Department of Health and Human Services we conducted an air quality study to measure the impact of a WSEP on indoor and neighborhood levels of wood combustion products. Twenty households engaged …

Synthesis And Assessment Of Radiotherapy-Enhancing Nanoparticles, Hayden Winter

Dissertations and Theses

Radiation Therapy (RT) is a common treatment for cancerous lesions that acts by ionizing matter in the affected tissue, causing cell death. The disadvantage of RT is that it is most often delivered via an external beam of radiation which must pass through healthy tissues to reach the target site, ionizing matter within healthy tissues as well. To address this drawback, techniques are being developed for increasing RT-induced cell death in a target tissue while minimizing cell death in surrounding tissues. This effect is known as radiation dose enhancement or RT enhancement.

The approach to RT enhancement studied in this …

Optimized Xanthene-Based Probes For Pancreatic Cancer Imaging, Ian Ruramai Munhenzva

Dissertations and Theses

Pancreatic Ductal Adenocarcinoma (PDAC) is one of the deadliest human malignancies with an extremely poor 5-year survival rate of below 5%. Surgical resection is the most effective treatment of choice because chemotherapy and radiation therapy do not improve life expectancy. Residual tumor after PDAC surgery is common due to a lack of PDAC targeted intraoperative contrast agents to confirm clear margins.

Fluorescence imaging has the potential to improve surgery outcome and PDAC patients' survival rate via the use of highly PDAC-specific molecular probes to facilitate tumor identification. This thesis describes the application of a focused library of benzoxanthene fluorophores for …