Engineering Commons^™

Microstructure Evolution During Compaction Of Powder Blends, Ayush Giri, Marcial Gonzalez, Yasasvi Bommire

The Summer Undergraduate Research Fellowship (SURF) Symposium

Powder compaction is a manufacturing technology used to transform powder particles into a solid material with unique anisotropic microstructure and low porosity. It is widely used by pharmaceutical companies to manufacture tablets with desired properties. These properties are the result of the microstructure obtained during the compaction process. Therefore, it is imperative to understand the mechanics underneath the constituent granular particles that eventually contribute to properties of the manufactured tablets. Computational simulation tools have been developed in the past to study powder compaction for pharmaceutical tablets. However, most of the already existing tools limit their scope to study individual particles …