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Epigenetics

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Mild Cognitive Impairment And Alzheimer’S Disease Detection And Testing Interface (Mci-Addti) Modeller10.4 Integrating Structure-Function Prediction Modules, Grant Galileo Jacobson Jan 2023

Mild Cognitive Impairment And Alzheimer’S Disease Detection And Testing Interface (Mci-Addti) Modeller10.4 Integrating Structure-Function Prediction Modules, Grant Galileo Jacobson

Master's Projects

In the population of adult human patients who over express Beta and Tau Amyloids, it is unclear why 40% of them do not have Alzheimer’s Disease (AD), when all patients with AD have an overexpression of Beta and Tau Amyloids. The MCI-AD-DTI project’s epigenetic pipeline is an evolving computation tool that seeks epigenetic-related information related to the observed disparity. The MCI-AD-DTI’s epigenetic pipeline’s ability to identify mutations currently relies solely on PyPDB for verification of its protein functionality evaluation. The assessment process of the industry standard application, Modeller10.4, is independent from the current epigenetic pipeline’s protein evaluation algorithm. Thus, this …