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Rodent Sperm Analysis In Field-Based Ecological Risk Assessment: Pilot Study At Ravenna Army Ammunition Plant, Ravenna, Ohio, Lawrence V. Tannenbaum, Matthew Bazar, Melanie S. Hawkins, Barney W. Cornaby, Elizabeth A. Ferguson, L. Chantelle Carroll, Patrick F. Ryan
Rodent Sperm Analysis In Field-Based Ecological Risk Assessment: Pilot Study At Ravenna Army Ammunition Plant, Ravenna, Ohio, Lawrence V. Tannenbaum, Matthew Bazar, Melanie S. Hawkins, Barney W. Cornaby, Elizabeth A. Ferguson, L. Chantelle Carroll, Patrick F. Ryan
US Army Research
Ecological risk assessment (ERA) guidance recommends that field-truthing efforts proceed when modeled hazard quotients (HQs) suggest that toxicological effects are occurring to site receptors. To date, no field methods have been proposed by the regulatory community that can lead to definitive determinations of acceptable or unacceptable risk for birds and mammals, the two terrestrial classes of receptors that are commonly assessed using the HQ method. This paper describes rodent sperm analysis (RSA) as a viable method to be applied in the field at sites with historical contamination. RSA is capable of detecting biological differences that bear on reproduction, a highly …