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Au@Tio2 Nanocomposites Synthesized By X-Ray Radiolysis As Potential Radiosensitizers, Maria C. Molina Higgins
Au@Tio2 Nanocomposites Synthesized By X-Ray Radiolysis As Potential Radiosensitizers, Maria C. Molina Higgins
Theses and Dissertations
Radiosensitization is a novel targeted therapy strategy where chemical compounds are being explored to enhance the sensitivity of the tissue to the effects of ionizing radiation. Among the different radiosensitizers alternatives, nanomaterials have shown promising results by enhancing tumor injury through the production of free radicals and reactive oxygen species (ROS). In this work, Gold-supported titania (Au@TiO2) nanocomposites were synthesized through an innovative strategy using X-ray irradiation, and their potential as radiosensitizers was investigated. Radiosensitization of Au@TiO2 nanocomposites was assessed by monitoring the decomposition of Methylene Blue (MB) under X-ray irradiation in the presence of the nanomaterial. …