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Full-Text Articles in Engineering

Task-Specific And General Cognitive Effects In Chiari Malformation Type I, Philip Allen, James Houston, Joshua Pollock, Christopher Buzzelli, Xuan Li, A. Harrington, Bryn Martin, Francis Loth, Mei-Ching Lien, Jahangir Maleki, Mark Luciano Apr 2015

Task-Specific And General Cognitive Effects In Chiari Malformation Type I, Philip Allen, James Houston, Joshua Pollock, Christopher Buzzelli, Xuan Li, A. Harrington, Bryn Martin, Francis Loth, Mei-Ching Lien, Jahangir Maleki, Mark Luciano

Dr. Bryn Martin

Our objective was to use episodic memory and executive function tests to determine whether or not Chiari Malformation Type I (CM) patients experience cognitive dysfunction.


The Impact Of Spinal Cord Nerve Roots And Denticulate Ligaments On Cerebrospinal Fluid Dynamics In The Cervical Spine, Soroush Heidari Paylavian, Theresia Yiallourou, R. Shane Tubbs, Alexander C. Bunck, Francis Loth, Bryn A. Martin, Mark Goodin, Mehrdad Raisee Apr 2015

The Impact Of Spinal Cord Nerve Roots And Denticulate Ligaments On Cerebrospinal Fluid Dynamics In The Cervical Spine, Soroush Heidari Paylavian, Theresia Yiallourou, R. Shane Tubbs, Alexander C. Bunck, Francis Loth, Bryn A. Martin, Mark Goodin, Mehrdad Raisee

Dr. Bryn Martin

Cerebrospinal fluid (CSF) dynamics in the spinal subarachnoid space (SSS) have been thought to play an important pathophysiological role in syringomyelia, Chiari I malformation (CM), and a role in intrathecal drug delivery. Yet, the impact that fine anatomical structures, including nerve roots and denticulate ligaments (NRDL), have on SSS CSF dynamics is not clear. In the present study we assessed the impact of NRDL on CSF dynamics in the cervical SSS. The 3D geometry of the cervical SSS was reconstructed based on manual segmentation of MRI images of a healthy volunteer and a patient with CM. Idealized NRDL were designed …