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Potential Dual Imaging Nanoparticle: Gd2o3 Nanoparticle, Md Wasi Ahmad
Potential Dual Imaging Nanoparticle: Gd2o3 Nanoparticle, Md Wasi Ahmad
Dr. Mohammad Wasi Ahmad (Md Wasi Ahmad)
Gadolinium (Gd) is a unique and powerful element in chemistry and biomedicine which can be applied simultaneously to magnetic resonance imaging (MRI), X-ray computed tomography (CT), and neutron capture therapy for cancers. This multifunctionality can be maximized using gadolinium oxide (Gd2O3) nanoparticles (GNPs) because of the large amount of Gd per GNP, making both diagnosis and therapy (i.e., theragnosis) for cancers possible using only GNPs. In this study, the T1 MRI and CT dual imaging capability of GNPs is explored by synthesizing various iodine compound (IC) coated GNPs (IC-GNPs). All the IC-GNP samples showed stronger X-ray absorption and larger longitudinal …