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A Two-Temperature Model For Selective Photothermolysis Laser Treatment Of Port Wine Stains, D. Li, Guo-Xiang Wang, Y. He, K. Kelly, W. Wu, Y. Wang, Z. Ying Apr 2015

A Two-Temperature Model For Selective Photothermolysis Laser Treatment Of Port Wine Stains, D. Li, Guo-Xiang Wang, Y. He, K. Kelly, W. Wu, Y. Wang, Z. Ying

Dr. Guo-Xiang Wang

Selective photothermolysis is the basic principle for laser treatment of vascular malformations such as port wine stain birthmarks (PWS). During cutaneous laser surgery, blood inside blood vessels is heated due to selective absorption of laser energy, while the surrounding normal tissue is spared. As a result, the blood and the surrounding tissue experience a local thermodynamic non-equilibrium condition. Traditionally, the PWS laser treatment process was simulated by a discrete-blood-vessel model that simplifies blood vessels into parallel cylinders buried in a multi-layer skin model. In this paper, PWS skin is treated as a porous medium made of tissue matrix and blood …


A Three-Temperature Model Of Selective Photothermolysis For Laser Treatment Of Port Wine Stain Containing Large Malformed Blood Vessels, D. Li, Guo-Xiang Wang, Y. He, W. Wu, B. Chen Apr 2015

A Three-Temperature Model Of Selective Photothermolysis For Laser Treatment Of Port Wine Stain Containing Large Malformed Blood Vessels, D. Li, Guo-Xiang Wang, Y. He, W. Wu, B. Chen

Dr. Guo-Xiang Wang

As congenital vascular malformations, port wine stain (PWS) is composed of ectatic venular capillary blood vessels buried within healthy dermis. In clinic, pulsed dye laser (PDL) in visible band (e.g. 585 nm) together with cryogen spray cooling (CSC) have become the golden standard for treatment of PWS. However, due to the limited energy deposition of the PDL in blood, large blood vessels are likely to survive from the laser irradiation. As a result, complete clearance of the lesions is rarely achieved. Assuming the local thermal non-equilibrium in skin tissue during the laser surgery, a three-temperature model is proposed to treat …