Engineering Commons^™

Fluid Agitation Studies For Drug Product Containers Using Computational Fluid Dynamics, Matthew Hiroki Ichinose

Master's Theses

At Amgen, the Automated Vision Inspection (AVI) systems capture the movement of unwanted particles in Amgen's drug product containers. For quality inspection, the AVI system must detect these undesired particles using a high speed spin-stop agitation process. To better understand the fluid movements to swirl the particles away from the walls, Computational Fluid Dynamics (CFD) is used to analyze the nature of the two phase flow of air and a liquid solution.

Several 2-D and 3-D models were developed using Fluent to create simulations of Amgen's drug product containers for a 1 mL syringe, 2.25 mL syringe, and a 5 …

Simulation Of Radiation Flux From Thermal Fluid In Origami Tubes, Robert R. Bebeau

USF Tampa Graduate Theses and Dissertations

Spacecraft in orbit experience temperature swings close to 240 K as the craft passes from the shadow of the Earth into direct sunlight. To regulate the craft’s internal energy, large radiators eject unwanted energy into space using radiation transfer. The amount of radiation emitted is directly related to the topology of the radiator design. Deformable structures such as those made with origami tessellation patterns offer a mechanism to control the quantity of energy being emitted by varying the radiator shape. Three such patterns, the Waterbomb, Huffman Waterbomb, and Huffman Stars-Triangles, can be folded into tubes. Origami tubes offer greater control …

A Mathematical Model For Predicting Rotating Belt Filter Performance, Anthony Sherratt

Electronic Thesis and Dissertation Repository

Increased demand on wastewater treatment plants has motivated the development of new primary wastewater treatment techniques. Rotating belt filters (RBF) offer a spatially compact and lower cost solution. The goal of the present work is to develop a model that accurately predicts the flow rate capacity and removal efficiency of a generic RBF. Mesh resistance will be characterized using an idealized computational fluid dynamics (CFD) model of the mesh filter used in an RBF. To characterize the cake resistance, a gravity drainage column test was modeled and using the results from the CFD model, the cake resistance versus filtered volume …

Implementing Large Eddy Simulation To Numerical Simulation Of Optical Wave Propagation, Diego Alberto Lozano Jimenez

Open Access Theses & Dissertations

In this study, we want to simulate long-range laser propagation in atmospheric turbulence. The numerical simulations are carried out to study the impact of strong atmospheric turbulence in spatial, temporal, and related spectral domains. The first section of this study will be concerned with modeling this numerical simulation in Kolmogorov and non-Kolmogorov spectrum. To validate our numerical simulation, we will compare the statistical parameter to theoretical approximation in both Kolmogorov and non-Kolmogorov spectrums. Once the code is validated, we want to integrate Large Eddy Simulation (LES) turbulence modeling. LES simulations allowa us to study strong fluid turbulence and can predict …

Data-Driven Predictive Framework For Modeling Complex Multi-Physics Engineering Applications, Arturo Schiaffino Bustamante

Open Access Theses & Dissertations

Computational models are often encountered in multiple engineering application, such as structural design, material science, heat transfer and fluid dynamics. These simulations offer the engineers the capability of understanding complex physical situations before putting them to practice, either through experimentation or prototyping. The current advances in computational sciences, hardware architecture, software development and big data technology, have allowed the construction of sturdy predicting frameworks for analyzing a wide array of natural phenomena across different disciplines, either through the implementation of statistical methods, such as big data, and uncertainty quantification, or through high performance computing of a numerical model. The objective …

Numerical Modeling Of Capillary-Driven Flow In Open Microchannels: An Implication Of Optimized Wicking Fabric Design, Mehrad Gholizadeh Ansari

Masters Theses

"The use of microfluidics to transfer fluids without applying any exterior energy source is a promising technology in different fields of science and engineering due to their compactness, simplicity and cost-effective design. In geotechnical engineering, to increase the soil's strength, hydrophilic wicking fibers as type of microfluidics have been employed to transport and drain water out of soil spontaneously by taking advantage of natural capillary force without using any pumps or other auxiliary devices. The objective of this study is to understand the scientific mechanisms of the capability for wicking fiber to drain both gravity and capillary water out of …