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Full-Text Articles in Engineering
The Effects Of Obesity On Resultant Knee Joint Loads For Gait And Cycling, Juan Gutierrez-Franco
The Effects Of Obesity On Resultant Knee Joint Loads For Gait And Cycling, Juan Gutierrez-Franco
Master's Theses
Osteoarthritis (OA) is a degenerative disease of cartilage and bone tissue and the most common form of arthritis, accounting for US$ 10.5 billion in hospital charges in 2006. Obesity (OB) has been linked to increased risk of developing knee OA due to increased knee joint loads and varus-valgus misalignment. Walking is recommended as a weight-loss activity but it may increase risk of knee OA as OB gait increases knee loads. Cycling has been proposed as an alternative weight-loss measure, however, lack of studies comparing normal weight (NW) and OB subjects in cycling and gait hinder identification of exercises that may …
Walking Simulator Mechanism, Titus Lungu, Igor Tachynskyy, Omri Tayyara
Walking Simulator Mechanism, Titus Lungu, Igor Tachynskyy, Omri Tayyara
The Downtown Review
This paper presents the design, simulation, and kinematic evaluation of a mechanism aimed at simulating both the motion and ground reaction forces produced by a human foot while walking. Such a mechanism can be used to test the durability of shoes through life cycle analysis. In attempting to mimic the physical motion of the human foot as closely as possible, the forces experienced by the human foot were also accurately replicated through the incorporation of a non-stationary testing platform. As is shown in the paper, this testing environment allows for simple adjustments to be made in order to simulate different …
Influence Of Shear Stress Magnitude And Direction On Atherosclerotic Plaque Composition, Ryan M. Pedrigi, Vikram V. Mehta, Sandra M. Bovens, Zahra Mohri, Christian Bo Poulsen, Willy Gsell, Jordi L. Tremoleda, Leila Towhidi, Ranil De Silva, Enrico Petretto, Rob Krams
Influence Of Shear Stress Magnitude And Direction On Atherosclerotic Plaque Composition, Ryan M. Pedrigi, Vikram V. Mehta, Sandra M. Bovens, Zahra Mohri, Christian Bo Poulsen, Willy Gsell, Jordi L. Tremoleda, Leila Towhidi, Ranil De Silva, Enrico Petretto, Rob Krams
Department of Mechanical and Materials Engineering: Faculty Publications
The precise flow characteristics that promote different atherosclerotic plaque types remain unclear. We previously developed a blood flow-modifying cuff for ApoE−/− mice that induces the development of advanced plaques with vulnerable and stable features upstream and downstream of the cuff, respectively. Herein, we sought to test the hypothesis that changes in flow magnitude promote formation of the upstream (vulnerable) plaque, whereas altered flow direction is important for development of the downstream (stable) plaque. We instrumented ApoE−/− mice (n=7) with a cuff around the left carotid artery and imaged them with micro-CT (39.6 μm resolution) eight to nine weeks …