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Full-Text Articles in Engineering

Development Of A Low Cost Handheld Microfluidic Phosphate Colorimeter For Water Quality Analysis, Sean C. Kaylor Aug 2009

Development Of A Low Cost Handheld Microfluidic Phosphate Colorimeter For Water Quality Analysis, Sean C. Kaylor

Master's Theses

This thesis describes the design, fabrication, and testing process for a microfluidic phosphate colorimeter utilized for water quality analysis. The device can be powered by, and interfaced for data collection with, a common cell phone or laptop to dramatically reduce costs. Unlike commercially available colorimeters, this device does not require the user to measure or mix sample and reagent. A disposable poly(dimethylsiloxane) (PDMS) microfluid chip, powered by an absorption pumping mechanism, was used to draw water samples, mix the sample at a specific ratio with a molybdovanadate reagent, and load both fluids into an onboard cuvette for colorimetric analysis. A …


Factors Affecting Redox Magnetohydrodynamics For Flow In Small Volumes, Matthew D. Gerner Aug 2009

Factors Affecting Redox Magnetohydrodynamics For Flow In Small Volumes, Matthew D. Gerner

Graduate Theses and Dissertations

Lab-on-a-chip technologies offer the possibility of developing analytical devices that are low-cost, portable, disposable, fast, and operable by non-technical personnel. Such devices require automated methods to manipulate ultra-small volumes (picoliters) of samples and solution, including pumping, stirring, and positioning. Current methods for ultra-small volume microfluidics have limitations that restrict their use including high voltage requirements, disadvantageous flow profiles or rates, and relatively complicated fabrication due to mechanical parts. Redox magnetohydrodyanmics (RMHD) that utilizes permanent magnets for portability shows promise as a micropump with ease of switching flow direction, no moving parts, compatibility with both aqueous and non-aqueous solutions, low voltages …


Laminar And Turbulent Flow Of A Liquid Through Channels With Superhydrophobic Walls Exhibiting Alternating Ribs And Cavities, Brady L. Woolford Mar 2009

Laminar And Turbulent Flow Of A Liquid Through Channels With Superhydrophobic Walls Exhibiting Alternating Ribs And Cavities, Brady L. Woolford

Theses and Dissertations

There is significant interest in reducing the frictional resistance that occurs along a surface in contact with a liquid. A novel approach to reducing the frictional resistance across a liquid-solid interface is the use of superhydrophobic surfaces. superhydrophobic surfaces are created in this work by the use of micro-fabrication techniques where systematic roughness is fabricated on a substrate surface which is subsequently treated with a hydrophobic coating. This work reports an experimental study of superhydrophobic surfaces used to reduce drag in both laminar and turbulent channel flows. In the laminar flow regime reductions in frictional resistance greater than 55% were …


A Multi-Function, Disposable, Microfluidic Module For Mutation Detection, Tae Yoon Lee Jan 2009

A Multi-Function, Disposable, Microfluidic Module For Mutation Detection, Tae Yoon Lee

LSU Doctoral Dissertations

Recognition of point mutations in a codon 12 of the K-ras gene, most frequently observed, is considered to be useful in the early diagnosis of several types of the human cancers. We have developed a multifunction, disposable, microfluidic module which detects low-abundant point mutations in human genomic DNA in modular architecture. Each functional component including a microfluidic PCR reactor, a passive diffusional micromixer reactor, and a microfluidic LDR reactor was separately designed and fabricated. Fluidic interconnects were also developed to make a fluidic passage between the functional components. Polycarbonate substrates were micro-molded, using hot embossing with micro-milled brass mold inserts …


Multiphase Flows In Polymer Microfluidic Systems, Namwon Kim Jan 2009

Multiphase Flows In Polymer Microfluidic Systems, Namwon Kim

LSU Doctoral Dissertations

Continuous delivery of segmented reagents using pressure-driven multiphase flow in microchannels is a promising technology for high throughput microfluidic bioassays. Separation and encapsulation of the target reagents with another inert fluid provide many advantages over single phase flow in microfluidic applications of biotechnology. In order to achieve these advantages and control these multiphase flows, it is necessary to understand their generation and transport characteristics as influenced by geometrical miniaturization, channel wall properties, the effects of surfactants and operating conditions. For gas-liquid two-phase flow, dry air and deionized water were driven into hot embossed PMMA microchannels with 200 μm square test …