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Development Of A Pdms Based Micro Total Analysis System For Rapid Biomolecule Detection, Balaji Srinivasan Venkatesh
Development Of A Pdms Based Micro Total Analysis System For Rapid Biomolecule Detection, Balaji Srinivasan Venkatesh
Graduate Theses and Dissertations
The emerging field of micro total analysis system powered by microfluidics is expected to revolutionize miniaturization and automation for point-of-care-testing systems which require quick, efficient and reproducible results. In the present study, a PDMS based micro total analysis system has been developed for rapid, multi-purpose, impedance based detection of biomolecules. The major components of the micro total analysis system include a micropump, micromixer, magnetic separator and interdigitated electrodes for impedance detection. Three designs of pneumatically actuated PDMS based micropumps were fabricated and tested. Based on the performance test results, one of the micropumps was selected for integration. The experimental results …