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Full-Text Articles in Engineering
3d-Printed Biomimetic Bioactive Glass Scaffolds For Bone Regeneration In Rat Calvarial Defects, Krishna C. R. Kolan, Yue-Wern Huang, Julie A. Semon, Ming-Chuan Leu
3d-Printed Biomimetic Bioactive Glass Scaffolds For Bone Regeneration In Rat Calvarial Defects, Krishna C. R. Kolan, Yue-Wern Huang, Julie A. Semon, Ming-Chuan Leu
Biological Sciences Faculty Research & Creative Works
The pore geometry of scaffold intended for the use in the bone repair or replacement is one of the most important parameters in bone tissue engineering. It affects not only the mechanical properties of the scaffold but also the amount of bone regeneration after implantation. Scaffolds with five different architectures (cubic, spherical, x, gyroid, and diamond) at different porosities were fabricated with bioactive borate glass using the selective laser sintering (SLS) process. The compressive strength of scaffolds with porosities ranging from 60% to 30% varied from 1.7 to 15.5 MPa. The scaffold's compressive strength decreased significantly (up to 90%) after …
Selective Laser Sintering Of Bioactive Glass Scaffolds And Their Biological Assessment For Bone Repair, Krishna C. R. Kolan
Selective Laser Sintering Of Bioactive Glass Scaffolds And Their Biological Assessment For Bone Repair, Krishna C. R. Kolan
Doctoral Dissertations
"Bone scaffold fabrication using powder-bed based additive manufacturing techniques, like the selective laser sintering (SLS) process, provides control over pore interconnectivity, pore geometry, and the overall shape of the scaffold, which aids in repairing different regions of the bone. The main objectives of this dissertation were to develop bioactive glass (BG) scaffolds using the SLS process and evaluate the scaffolds for their effectiveness in bone repair both in vitro and in vivo. 13-93 glass, a silicate based BG, and 13-93B3 glass, a borate based BG, are designed to accelerate the body's natural ability to heal itself and are used …
Effect Of Architecture And Porosity On Mechanical Properties Of Borate Glass Scaffolds Made By Selective Laser Sintering, Krishna C. R. Kolan, Ming-Chuan Leu, Greg Hilmas, Taylor Comte
Effect Of Architecture And Porosity On Mechanical Properties Of Borate Glass Scaffolds Made By Selective Laser Sintering, Krishna C. R. Kolan, Ming-Chuan Leu, Greg Hilmas, Taylor Comte
Mechanical and Aerospace Engineering Faculty Research & Creative Works
The porosity and architecture of bone scaffolds, intended for use in bone repair or replacement, are two of the most important parameters in the field of bone tissue engineering. The two parameters not only affect the mechanical properties of the scaffolds but also aid in determining the amount of bone regeneration after implantation. Scaffolds with five different architectures and four porosity levels were fabricated using borate bioactive glass (13-93B3) using the selective laser sintering (SLS) process. The pore size of the scaffolds varied from 400 to 1300 μm. The compressive strength of the scaffolds varied from 1.7 to 15.5 MPa …
Effect Of Particle Size, Binder Content And Heat Treatment On Mechanical Properties Of 13-93 Bioactive Glass Scaffolds, Krishna C. R. Kolan, Ming-Chuan Leu, Greg Hilmas, Mariano Garcia Velez
Effect Of Particle Size, Binder Content And Heat Treatment On Mechanical Properties Of 13-93 Bioactive Glass Scaffolds, Krishna C. R. Kolan, Ming-Chuan Leu, Greg Hilmas, Mariano Garcia Velez
Mechanical and Aerospace Engineering Faculty Research & Creative Works
Particle size, binder content and the post-processing schedule are important parameters that affect the microstructure, and, hence, the mechanical properties of parts produced using the indirect selective laser sintering process. 13-93 bioactive glass, with mean particle sizes ranging from 10 μm to 44 μm, is mixed with different amounts of stearic acid binder to fabricate green scaffolds. Through the design of the post-processing schedule, the time required for postprocessing the green scaffolds is reduced from the initial 80 hrs to 12 hrs. The compressive strength varies from 41 MPa for a part with~60% porosity to 157 MPa for a part …