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Synthesis And Characterization Of Nanocrystalline Hydroxyapatite Powder; And The Effects Of Oxide-Based Sintering Additives On Tricalcium Phosphate, Himesh A. Bhatt

Electronic Theses and Dissertations

Calcium phosphate (CP) materials have been used extensively for bone replacement and augmentation due to their similarity to the mineral component of bone. In addition to being non-toxic, they are biocompatible, not recognized as foreign materials in vivo, and most importantly, exhibit osteoconductive behavior, being able to help in bone formation during healing. CPs form an intimate physicochemical bond with the host tissue, termed osseointegration. However the main limitation of calcium phosphates is their inherent brittle nature and poor mechanical performance under complex stress states. As a result, these materials have been used clinically only in non-load-bearing applications, primarily as …