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Full-Text Articles in Engineering

Analyzing The Effects Of E-Hook Peptides On Kinesin-1, Ashton Ward Murrah, Baylee Hope Howard May 2021

Analyzing The Effects Of E-Hook Peptides On Kinesin-1, Ashton Ward Murrah, Baylee Hope Howard

Honors Theses

Cancer is the second leading cause of death in the United States. Cancerous growth is a result of oncogenes, or mutated genes that increase the rate of cell division in an uncontrolled manner. Cell division, which consists of mitosis and cytokinesis phases, is dependent upon the active movement of kinesin motor proteins along microtubules to rearrange the cytoskeleton for equitable distribution of genetic material to daughter cells. As kinesins are vital to this process, if we could prevent kinesin from binding to the microtubules, cell division would cease.

The goal of this study is to develop a method to prevent …


Surface-Eroding Drug Delivery Films For Sequential And/Or Intermittent Release Of Psychoactive Drugs, Jason Price Apr 2021

Surface-Eroding Drug Delivery Films For Sequential And/Or Intermittent Release Of Psychoactive Drugs, Jason Price

Honors Theses

ABSTRACT JASON BLAKE PRICE: Surface-Eroding Drug Delivery Films for Sequential and/or

Intermittent Release of Psychoactive Drugs For patients with psychiatric diseases, adherence to medication schedules, medication

errors, and abuse are common issues. Promising new forms of therapy for these patients, such as micro-dosed lysergic acid diethylamide (LSD), where patients receive 10-20% of a full dose every third day, present further drug delivery challenges. Sequential or intermittent release of drugs from an implanted device could ensure long-term drug compliance, automate drug dosing during the life of the implant, and eliminate potential for abuse and medication errors. To this end, we generated …


Velocity Distribution And Stress Analysis In A Continuous Exchange Cell-Free Protein Synthesis System, Grace Nguyen Apr 2021

Velocity Distribution And Stress Analysis In A Continuous Exchange Cell-Free Protein Synthesis System, Grace Nguyen

Honors Theses

No abstract provided.


Development And Mechanical Characterization Of A Composite Biomaterial Made From Agricultural Waste Reinforcement In A Fungal Mycelium Matrix., John Adam Howe Apr 2021

Development And Mechanical Characterization Of A Composite Biomaterial Made From Agricultural Waste Reinforcement In A Fungal Mycelium Matrix., John Adam Howe

Honors Theses

No abstract provided.


Artificial Reefs: A History, A Science, A Technology, Mairead D. Farrell Jan 2021

Artificial Reefs: A History, A Science, A Technology, Mairead D. Farrell

Honors Theses

Over the past 60 years, artificial reefs have expanded beyond the definition of a technology, and in turn have developed into a unique branch of marine science. To better emphasize this growth and separation, a brief history of artificial reef development and usage in chapter two shows some of the key shifts over time in this technology’s purpose and the materials used to achieve that goal. Likewise, to indicate the scientific development of artificial reefs as a branch of marine science, their usage for discovery and research is recorded in chapter three, along with the exponential increase in published scientific …