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Full-Text Articles in Engineering
Oxidase-Coupled Amperometric Glucose And Lactate Sensors With Integrated Electrochemical Actuation System, Jongwon Park, Chang-Soo Kim, Minsu Choi
Oxidase-Coupled Amperometric Glucose And Lactate Sensors With Integrated Electrochemical Actuation System, Jongwon Park, Chang-Soo Kim, Minsu Choi
Electrical and Computer Engineering Faculty Research & Creative Works
Unpredictable baseline drift and sensitivity degradation during continuous use are two of the most significant problems of biosensors including the amperometric glucose and lactate sensors. Therefore, the capability of on-demand in situ calibration/diagnosis of biochemical sensors is indispensable for reliable long-term monitoring with minimum attendance. Another limitation of oxidase enzyme-based biosensors is the dependence of enzyme activity on the background oxygen concentration in sample solution. In order to address these issues, the electrolytic generation of oxygen and hydrogen bubbles were utilized 1) to overcome the background oxygen dependence of glucose and lactate sensors and 2) to demonstrate the feasibility of …
Automated Oxidase-Coupled Amperometric Microsensor With Integrated Electrochemical Actuation System For Continuous Sensing Of Saccharoids, Yadunandana Yellambalase, Jongwon Park, Chang-Soo Kim, Minsu Choi, Nohpill Park, Fabrizio Lombardi
Automated Oxidase-Coupled Amperometric Microsensor With Integrated Electrochemical Actuation System For Continuous Sensing Of Saccharoids, Yadunandana Yellambalase, Jongwon Park, Chang-Soo Kim, Minsu Choi, Nohpill Park, Fabrizio Lombardi
Electrical and Computer Engineering Faculty Research & Creative Works
Recent developments for biosensors have been mainly focused on miniaturization and exploratory use of new materials. It should be emphasized that the absence of a novel "in-situ self-calibration/diagnosis technique" that is not connected to an external apparatus is a key obstacle to the realization of a biosensor for continuous use with minimum attendance. To address this deficiency, a novel needle-type biosensor system with fully automated operations is being developed, in which a novel oxidase-coupled amperometric sensor with oxygen depleting/generating actuator is interfaced with an electrochemical instrument and a perfusion system. Labview virtual instrument has been also developed to oversee the …
Manipulation Of Microenvironment With A Built-In Electrochemical Actuator In Proximity Of A Dissolved Oxygen Microsensor, Chang-Soo Kim, J. O. Fiering, C. W. Scarantino, H. Troy Nagle, Chae-Hyang Lee, Stefan Ufer
Manipulation Of Microenvironment With A Built-In Electrochemical Actuator In Proximity Of A Dissolved Oxygen Microsensor, Chang-Soo Kim, J. O. Fiering, C. W. Scarantino, H. Troy Nagle, Chae-Hyang Lee, Stefan Ufer
Electrical and Computer Engineering Faculty Research & Creative Works
Biochemical sensors for continuous monitoring require dependable periodic self diagnosis with acceptable simplicity to check its functionality during operation. An in-situ self-diagnostic technique for a dissolved oxygen microsensor is proposed in an effort to devise an intelligent microsensor system with an integrated electrochemical actuation electrode. With a built-in platinum microelectrode that surrounds the microsensor, two kinds of microenvironments, called the oxygen-saturated or oxygen-depleted phases, can be created by water electrolysis, depending on the polarity. The functionality of the microsensor can be checked during these microenvironment phases. The polarographic oxygen microsensor is fabricated on a flexible polyimide substrate (Kapton) and the …
An Intelligent Dissolved Oxygen Microsensor System With Electrochemically Actuated Fluidics, Chang-Soo Kim, Jongwon Park, Xinbo He
An Intelligent Dissolved Oxygen Microsensor System With Electrochemically Actuated Fluidics, Chang-Soo Kim, Jongwon Park, Xinbo He
Electrical and Computer Engineering Faculty Research & Creative Works
A new dissolved oxygen monitoring microsystem is proposed to achieve in situ intelligent self-calibration by using an electrochemically actuated fluidic system. The electrochemical actuation, based on water electrolysis, plays two critical roles in the proposed microsystem. First, the electrochemically generated gases serve as the calibrants for the in situ 2-point calibration/diagnosis procedure of the microsensor in a chip. Secondly, the electrochemical generation and collapse of gas bubbles provide the driving force of the bidirectional fluidic manipulation for sampling and dispensing of the sample solution. A microsystem including a dissolved oxygen microprobe, electrochemical actuators, and a fluidic structure are prepared by …
Electrochemical And Hydrodynamic Interferences On The Performance Of An Oxygen Microsensor With Built-In Electrochemical Microactuator, Chang-Soo Kim, Chae-Hyang Lee
Electrochemical And Hydrodynamic Interferences On The Performance Of An Oxygen Microsensor With Built-In Electrochemical Microactuator, Chang-Soo Kim, Chae-Hyang Lee
Electrical and Computer Engineering Faculty Research & Creative Works
An in situ self-diagnostic technique for a dissolved oxygen microsensor is proposed in an effort to devise an intelligent microsensor system with an integrated electro-chemical actuation electrode. With a built-in platinum microelectrode that surrounds the microsensor, two kinds of microenvironments (oxygen-saturated or oxygen-depleted phases) can be created by water electrolysis depending on the polarity. The functionality of the microsensor can be checked during these microenvironment phases. The polarographic oxygen microsensor is fabricated on a flexible polyimide substrate (Kapton/sup ©/) and the influences of electrochemical and hydrodynamic conditions on the sensor responses have been investigated.