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Full-Text Articles in Engineering
Novel Copper (Ii) Mediated Transfection Nano-Systems And Biological Properties Of Pyridinium Surfactants, Sarit Pal
Open Access Theses & Dissertations
Efficacy of gene therapy is relied upon the improvement of gene delivery vectors into mammalian cells. Although viral-based polynucleotide carriers are still considered as the most common method for gene delivery but the cost effectiveness, nonspecific lethal immune response has evoked the renaissance of non-viral synthetic delivery systems. An initial discovery by Felgnar et al showed Cationic Liposomes (CLs) (having an overall positive charge) when mixed with DNA to form CL-DNA complexes can enhance the transfer of polynucleotides into cells followed by its expression. Presently, a flurry of experimental works is taking place for the better understanding of structural characterization …
Method Development For A Chemical And Biological Analysis Of Glucocorticoids In Wastewater, Maria Carmen Lozano
Method Development For A Chemical And Biological Analysis Of Glucocorticoids In Wastewater, Maria Carmen Lozano
Open Access Theses & Dissertations
Glucocorticoids are a class of steroid hormones that can either be produced synthetically or naturally by the adrenal glands. The synthetic glucocorticoids are highly prescribed in the United States for their anti-inflammatory and immunosuppressive properties to treat a variety of ailments and diseases; however, these have been implicated in a number of adverse human conditions such as obesity, metabolic syndrome, immune-suppression, delayed puberty, adrenal insufficiency and Cushing Syndrome, among others. Ongoing research has shown that synthetic and natural hormones are transported to aquatic environments via mammalian excretion or wastewater effluent, and as a result, the release of glucocorticoids into the …
Manufacturing Nerve Guidance Conduits By Stereolithography For Use In Peripheral Nerve Regeneration, Mireya Aidee Perez
Manufacturing Nerve Guidance Conduits By Stereolithography For Use In Peripheral Nerve Regeneration, Mireya Aidee Perez
Open Access Theses & Dissertations
Nerve regeneration techniques have been studied in great depth in recent years. Peripheral nerve injuries, in particular, can be caused by accidents, falls, athletic injuries, etc. Current methods of repair include direct suturing of the 2 injured nerve ends or the use of autografts, when a nerve section is taken from another area of the body. Both methods have a series of limitations which have led researchers to study alternative methods of repair. Nerve guidance conduits may provide a viable solution because they can be modified and adapted to the patient's needs. Some conduits already exist on the market and …