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Full-Text Articles in Engineering

Quantifying Cartilage Composition And Arthrokinematics: Application To Short-Term Biomechanical Outcomes After Sports-Related Knee Injury And Surgery, John Curtis Ramsdell Jan 2023

Quantifying Cartilage Composition And Arthrokinematics: Application To Short-Term Biomechanical Outcomes After Sports-Related Knee Injury And Surgery, John Curtis Ramsdell

Graduate College Dissertations and Theses

The long-term consequence for many individuals who suffer ACL injury, especially when the meniscus suffers injury as well, is the development of early-onset osteoarthritis (OA), commonly referred to as post-traumatic OA (PTOA). Target therapies to reduce PTOA incidence are desperately needed, as upwards of 200,000 ACL injuries occur each year in the United States; however, therapeutic advancements are hindered by the lack of understanding for the mechanisms that drive PTOA onset and progression. A prevailing hypothesis is that post-surgical alterations to the injured knee’s arthrokinematics (the way the cartilage surfaces of the femur and tibia articulate) introduce an unusual loading …


Development Of A Portable Device For Quantifying Internal-External Rotational Laxity Of The Knee In Vivo, Haley Kuralt Jan 2023

Development Of A Portable Device For Quantifying Internal-External Rotational Laxity Of The Knee In Vivo, Haley Kuralt

Graduate College Dissertations and Theses

Osteoarthritis (OA) is the leading cause of mobility-related disability. Post-traumatic osteoarthritis (PTOA) is a form of OA that occurs after an acute injury to the affected joint. In the case of the knee, rupture of the anterior cruciate ligament (ACL) is the most common acute injury. ACL injury occurs in sports that involve cutting and pivoting motions, such as soccer, football, and skiing. Many patients opt to undergo ACL reconstructive surgery (ACLR) so that they may return to their sport with restored knee stability and function. Unfortunately, ACLR does not completely restore the knee to its original state, resulting in …