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Dr. Guo-Xiang Wang

Biological physics

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Full-Text Articles in Engineering

Effects Of Particle's Off-Axis Position, Shape, Orientation And Entry Position On Resistance Changes Of Micro Coulter Counting Devices, Zhenpeng Qin, Jiang Zhe, Guo-Xiang Wang Apr 2015

Effects Of Particle's Off-Axis Position, Shape, Orientation And Entry Position On Resistance Changes Of Micro Coulter Counting Devices, Zhenpeng Qin, Jiang Zhe, Guo-Xiang Wang

Dr. Guo-Xiang Wang

With the recent advance in micro/nano-fabrication technology, micro Coulter counters have been widely used in detecting and characterizing micro- and nanoscale objects. In this paper, the electrical resistance change during translocation of a non-conducting particle through a channel is studied numerically. The numerical results are validated by proven analytical results available in the literature. The effects of particle's off-axis position, shape and orientation, and entry position are studied for particles with a large dynamic range. From the numerical results, a new fitted correlation is proposed that can accurately predict the resistance change caused by off-axis spherical particles regardless of their …