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Full-Text Articles in Engineering
Electrospinning For Tissue Engineering Scaffolds, J. Lannutti, Darrell Reneker, T. Ma, D. Tomasko, D. Farson
Electrospinning For Tissue Engineering Scaffolds, J. Lannutti, Darrell Reneker, T. Ma, D. Tomasko, D. Farson
Darrell Hyson Reneker
Tissue engineering involves fabrication of three-dimensional scaffolds to support cellular in-growth and proliferation. The goal: generation of ‘neotissues’ that the body can adapt to carry out physiological function. To achieve this generation of scaffolds having tailored, biomimetic (across multiple scales) geometries has become important. The functional complexity of electrospun scaffolds provides significant advantages over other techniques; however, improvements are required before optimal utilization in vivo becomes routine. Cells on such surfaces are sensitive to topography. Electrospinning can be altered to influence either (1) the surface topography of the fibers themselves or (2) the larger topography of the ‘web’ of spun …
Electrospun Nanofibers From A Porous Hollow Tube, J. Varahbas, George Chase, Darrell Reneker
Electrospun Nanofibers From A Porous Hollow Tube, J. Varahbas, George Chase, Darrell Reneker
Darrell Hyson Reneker
Single electrospinning jets are known to have low production rates. A 0.1 m2 nonwoven mat containing 1 g of 100 nm fibers may take several days to create from a single jet. Inexpensive methods of higher production rates are needed for laboratory research applications. In this paper we present experimental results of many simultaneous electrospinning jets from the surface of tube having a porous wall. The pores in the wall are small and resist the flow of the polymer. Holes drilled half way into the wall of the tube provide points of reduced flow resistance. A polymer solution of 15 …