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Full-Text Articles in Engineering
Development Of A Point-Of-Use Testing Platform For Detecting Bacteria Infection In Raw Milk, Xin Xia
Development Of A Point-Of-Use Testing Platform For Detecting Bacteria Infection In Raw Milk, Xin Xia
Masters Theses
The detection and quantification of bacteria are essential to environment and food quality monitoring. Escherichia coli (E. coli) is a common pathogen, also a causative agent of mastitis. Traditional methods usually require samples to be tested in a laboratory. However, sending samples to remote lab increases the cost of time and money spent on delivery. Sometimes, samples can degrade during this long progress and cause inaccuracy. A low cost and reusable sensor is designed to perform on-site quantification. The sensor composed of two layers of asymmetrical mesh electrodes, which is used in coordination magnetic microparticles functionalized with bacterium-specific antibody. Immunological …
Development Of A Low Cost Biosensing Platform For Highly Sensitive And Specific On-Site Detection Of Pathogens And Infections, Cheng Cheng
Doctoral Dissertations
A highly sensitive, specific, real time, and field-deployable surveillance tool is critical to the control of pathogens and infections, as well as ecological impact of chemicals exposure. This work investigates the development of a low cost biosensing platform that can be used for viral disease diagnosis and chemical detection. The sensing mechanism is known as AC electrokinetics (ACEK) capacitive sensing. By applying an inhomogeneous AC electric field on sensor electrodes, positive dielectrophoresis is induced to accelerate the travel of analytes. The same applied AC signal also directly measures the capture of target by the probe on sensor surface. The realized …