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Numerical And Analytical Modeling To Determine Performance Trade-Offs In Hydrogel-Based Ph Sensors, Piyush Dak, Muhammad Ashraful Alam

Birck and NCN Publications

Hydrogel based pH sensors are promising candidates for implantable sensors due to their low-cost and biocompatibility. Despite their commercial potential and numerous theoretical/experimental reports, the trade-offs between different performance parameters are not well understood, and explicitly stated. In this work, we develop a numerical and analytical framework to show that there is a fundamental trade-off between the performance parameters i.e. sensitivity/dynamic range vs. response-time/response-asymmetry in hydrogel sensors under constrained swelling conditions. Specifically, we consider the effect of the gel parameters, such as the ionizable group density ( N_f) and its dissociation constant ( K_a), on the …