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Model-Driven Safety Analysis Of Closed-Loop Medical Systems, Miroslav Pajic, Rahul Mangharam, Oleg Sokolsky, David Arney, Julian M. Goldman, Insup Lee
Model-Driven Safety Analysis Of Closed-Loop Medical Systems, Miroslav Pajic, Rahul Mangharam, Oleg Sokolsky, David Arney, Julian M. Goldman, Insup Lee
Oleg Sokolsky
In modern hospitals, patients are treated using a wide array of medical devices that are increasingly interacting with each other over the network, thus offering a perfect example of a cyber-physical system. We study the safety of a medical device system for the physiologic closed-loop control of drug infusion. The main contribution of the paper is the verification approach for the safety properties of closed-loop medical device systems. We demonstrate, using a case study, that the approach can be applied to a system of clinical importance. Our method combines simulation-based analysis of a detailed model of the system that contains …