Engineering Commons^™

Design Of Asic Based Electrical Impedance Tomography Microendoscopic System For Prostate Cancer Surgical Marginal Assessment, Mohsen Shahghasemi

Dartmouth College Ph.D Dissertations

Prostate cancer is the second most common cancer in the United States. It is typically treated by surgically excising the cancerous section of the prostate. Because there is not always a visible distinction between the healthy and cancerous sections, surgery often leaves some cancerous tissue behind. This is referred to as a positive surgical margin and it requires adjuvant treatment with adverse side effects. Electrical impedance tomography (EIT) is a low-cost low-form-factor method that can be used to assess surgical marginal intraoperatively to ensure that no cancerous tissue is left behind. EIT-based surgical margin assessment works on the principle that …

Design Of A Burst Mode Ultra High-Speed Low-Noise Cmos Image Sensor, Xin Yue

Dartmouth College Ph.D Dissertations

Ultra-high-speed (UHS) image sensors are of interest for studying fast scientific phenomena and may also be useful in medicine. Several published studies have recently achieved frame rates of up to millions of frames per second (Mfps) using advanced processes and/or customized processes.

This thesis presents a burst-mode (108 frames) UHS low-noise CMOS image sensor (CIS) based on charge-sweep transfer gates in an unmodified, standard 180 nm front-side-illuminated CIS process. By optimizing the photodiode geometry, the 52.8 μm pitch pixels with 20x20 μm^2 of active area, achieve a charge-transfer time of less than 10 ns. A proof-of-concept CIS was designed and …

Piezoelectric And Conductive Polymer Based Flexible Devices Enabling Cardiovascular Health Sensing And Energy Harvesting, Andrew Closson

Dartmouth College Ph.D Dissertations

Piezoelectric materials show great promise for low-power wearable and implantable sensing, but their rigidity makes it challenging to integrate them with biological tissue. To address this, researchers have started exploring polymer-based functional materials that offer flexibility and are suitable for interfacing with the human body. However, these materials are still in their early stages, and a framework is necessary to illustrate how these materials, in conjunction with novel fabrication techniques and device designs, can enable the development of multi-functional sensing and energy harvesting devices.

This thesis utilizes highly scalable fabrication methods for functional polymers to build and test a flexible …

Sensitive And Makeable Computational Materials For The Creation Of Smart Everyday Objects, Te-Yen Wu Mr

Dartmouth College Ph.D Dissertations

The vision of computational materials is to create smart everyday objects using the materi- als that have sensing and computational capabilities embedded into them. However, today’s development of computational materials is limited because its interfaces (i.e. sensors) are unable to support wide ranges of human interactions , and withstand the fabrication meth- ods of everyday objects (e.g. cutting and assembling). These barriers hinder citizens from creating smart every day objects using computational materials on a large scale.

To overcome the barriers, this dissertation presents the approaches to develop compu- tational materials to be 1) sensitive to a wide variety of …

An Adaptive Multiple-Object Tracking Architecture For Long-Duration Videos With Variable Target Density, Joachim Lohn-Jaramillo

Dartmouth College Ph.D Dissertations

Multiple-Object Tracking (MOT) methods are used to detect targets in individual video frames, e.g., vehicles, people, and other objects, and then record each unique target’s path over time. Current state-of-the-art approaches are extremely complex because most rely on extracting and comparing visual features at every frame to track each object. These approaches are geared toward high-difficulty-tracking scenarios, e.g., crowded airports, and require expensive dedicated hardware, e.g., Graphics Processing Units. In hardware-constrained applications, researchers are turning to older, less complex MOT methods, which reveals a serious scalability issue within the state-of-the-art. Crowded environments are a niche application for MOT, i.e., there …