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Full-Text Articles in Engineering
Photographic Studies Of Laser-Induced Bubble Formation In Absorbing Liquids And On Submerged Targets: Implications For Drug Delivery With Microsecond Laser Pulses, Hanqun Shangguan, Lee W. Casperson, Dennis L. Paisley, Scott A. Prahl
Photographic Studies Of Laser-Induced Bubble Formation In Absorbing Liquids And On Submerged Targets: Implications For Drug Delivery With Microsecond Laser Pulses, Hanqun Shangguan, Lee W. Casperson, Dennis L. Paisley, Scott A. Prahl
Electrical and Computer Engineering Faculty Publications and Presentations
Pulsed laser ablation of blood clots in a fluid-filled blood vessel is accompanied by an explosive evaporation process. The resulting vapor bubble rapidly expands and collapses to disrupt the thrombus (blood clot). The hydrodynamic pressures following the bubble expansion and collapse can also be used as a driving force to deliver clot-dissolving agents into thrombus for enhancement of laser thrombolysis. Thus, the laser-induced bubble formation plays an important role in the thrombus removal process. We investigate the effects of boundary configurations and materials on bubble formation with time-resolved flash photography and high-speed photography. Potential applications in drug delivery using microsecond …
Few-Cycle Pulses In Two-Level Media, Lee W. Casperson
Few-Cycle Pulses In Two-Level Media, Lee W. Casperson
Electrical and Computer Engineering Faculty Publications and Presentations
Techniques for producing, measuring, and applying ever shorter electromagnetic pulses are being developed for incorporation in a variety of modern high-speed systems. In many cases these pulses are at most a few cycles in length, and so-called half-cycle electromagnetic pulses are also widely employed. The interaction of such pulses with two-level media is considered here in detail, and these media are basic to many of the absorbing and amplifying configurations of optics and laser studies. Significant delays and distortion of the resulting polarization and population pulses can occur, and nonlinear optical effects are also revealed. The limitations of the parity, …