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Functionalization Of In-Plane Photonic Microcantilever Arrays For Biosensing Applications, Stanley J. Ness
Functionalization Of In-Plane Photonic Microcantilever Arrays For Biosensing Applications, Stanley J. Ness
Theses and Dissertations
Microcantilevers have been investigated as high sensitivity, label free biosensors for approximately 15 years. In nearly all cases, a thin gold film deposited on the microcantilevers is used as an intermediate attachment layer because of the convenience of thiol-gold chemistry. Unfortunately, this attachment chemistry can be unstable when used with complex sample media such as blood plasma. The Nordin group at BYU has recently developed an all-silicon in-plane photonic microcantilever (PMCL) technology to serve as a platform for label-free biosensing. It has the advantage of being readily scalable to simultaneous readout of many PMCLs in array format, and allows integration …
Characterization And Preliminary Demonstration Of Microcantilever Array Integrated Sensors, Ryan R. Anderson
Characterization And Preliminary Demonstration Of Microcantilever Array Integrated Sensors, Ryan R. Anderson
Theses and Dissertations
I characterize the behavior of microcantilever arrays which utilize the in-plane photonic transduction that I've previously developed and evaluate the performance of the microcantilever arrays in simple sensing scenarios with integrated microfluidics. First the thermal responses of microcantilevers with a variety of patterns of deposited gold films are compared. Using a scanning electron microscope, I observe the deflection thermal sensitivities of 300 µm long microcantilevers to be -170.82 nm/K for a full gold coating and -1.93 nm/K for no gold coating. Using the photonic transduction method I measure a thermal sensitivity of -1.46 nm/K for a microcantilever array with no …