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Full-Text Articles in Engineering
Adaptive Scaling Of Cluster Boundaries For Large-Scale Social Media Data Clustering, Lei Meng, Ah-Hwee Tan, Donald C. Wunsch
Adaptive Scaling Of Cluster Boundaries For Large-Scale Social Media Data Clustering, Lei Meng, Ah-Hwee Tan, Donald C. Wunsch
Research Collection School Of Computing and Information Systems
The large scale and complex nature of social media data raises the need to scale clustering techniques to big data and make them capable of automatically identifying data clusters with few empirical settings. In this paper, we present our investigation and three algorithms based on the fuzzy adaptive resonance theory (Fuzzy ART) that have linear computational complexity, use a single parameter, i.e., the vigilance parameter to identify data clusters, and are robust to modest parameter settings. The contribution of this paper lies in two aspects. First, we theoretically demonstrate how complement coding, commonly known as a normalization method, changes the …
Bioinformatics Approaches To Single-Cell Analysis In Developmental Biology, Dicle Yalcin, Zeynep M. Hakguder, Hasan H. Otu
Bioinformatics Approaches To Single-Cell Analysis In Developmental Biology, Dicle Yalcin, Zeynep M. Hakguder, Hasan H. Otu
Department of Electrical and Computer Engineering: Faculty Publications
Individual cells within the same population show various degrees of heterogeneity, which may be better handled with single-cell analysis to address biological and clinical questions. Single-cell analysis is especially important in developmental biology as subtle spatial and temporal differences in cells have significant associations with cell fate decisions during differentiation and with the description of a particular state of a cell exhibiting an aberrant phenotype. Biotechnological advances, especially in the area of microfluidics, have led to a robust, massively parallel and multi-dimensional capturing, sorting, and lysis of single-cells and amplification of related macromolecules, which have enabled the use of imaging …