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Full-Text Articles in Engineering

Design Of A Novel Low - Cost, Portable, 3d Ultrasound System With Extended Imaging Capabilities For Point-Of-Care Applications, Michail Tsakalakis Jan 2015

Design Of A Novel Low - Cost, Portable, 3d Ultrasound System With Extended Imaging Capabilities For Point-Of-Care Applications, Michail Tsakalakis

Browse all Theses and Dissertations

Ultrasound Imaging (USI) or Medical Sonography (MS), as it is formally called, has been widely used in biomedical applications over the last decades. USI can provide clinicians with a thorough view of the internal parts of the human body, making use of sound waves of higher frequencies than humans can perceive. USI systems are considered highly portable and of low-cost, compared to other imaging modalities. However, despite those advantages, Ultrasound Systems (US) and especially 3D ones, have not been yet extensively utilized for Point-of-Care (POC) applications, due to numerous restrictions and artifacts that they currently present.

Hardware complexity and real-time …


Evaluation Of The Signature Molecular Descriptor With Blosum62 And An All-Atom Description For Use In Sequence Alignment Of Proteins, Lindsay M. Aichinger Jan 2015

Evaluation Of The Signature Molecular Descriptor With Blosum62 And An All-Atom Description For Use In Sequence Alignment Of Proteins, Lindsay M. Aichinger

Williams Honors College, Honors Research Projects

This Honors Project focused on a few aspects of this topic. The second is comparing the molecular signature kernels to three of the BLOSUM matrices (30, 62, and 90) to test the accuracy of the mathematical model. The kernel matrix was manipulated in order to improve the relationship by focusing on side groups and also by changing how the structure was represented in the matrix by increasing the initial height distance from the central atom (Height 1 and Height 2 included).

There were multiple design constraints for this project. The first was the comparison with the BLOSUM matrices (30, 62, …