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Engineering Commons

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Computer Engineering

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University of Louisville

2018

Deep learning

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Full-Text Articles in Engineering

End-To-End Learning Framework For Circular Rna Classification From Other Long Non-Coding Rnas Using Multi-Modal Deep Learning., Mohamed Chaabane May 2018

End-To-End Learning Framework For Circular Rna Classification From Other Long Non-Coding Rnas Using Multi-Modal Deep Learning., Mohamed Chaabane

Electronic Theses and Dissertations

Over the past two decades, a circular form of RNA (circular RNA) produced from splicing mechanism has become the focus of scientific studies due to its major role as a microRNA (miR) ac tivity modulator and its association with various diseases including cancer. Therefore, the detection of circular RNAs is a vital operation for continued comprehension of their biogenesis and purpose. Prediction of circular RNA can be achieved by first distinguishing non-coding RNAs from protein coding gene transcripts, separating short and long non-coding RNAs (lncRNAs), and finally pre dicting circular RNAs from other lncRNAs. However, available tools to distinguish circular …