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Civil and Environmental Engineering

University of South Carolina

Theses and Dissertations

Theses/Dissertations

Genetics

Publication Year

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Full-Text Articles in Engineering

Electric Freight Transportation System Planning And Truck Operation Optimizations, Xuanke Wu Oct 2023

Electric Freight Transportation System Planning And Truck Operation Optimizations, Xuanke Wu

Theses and Dissertations

The substantial demand for fossil fuel consumption is a significant contributor to greenhouse gas emissions, drawing considerable public attention to health and environmental problems. As a result, vehicle electrification is currently recognized as the most effective approach to reduce CO2 emissions from transportation. However, compared to traditional fossil fuel-powered vehicles, electric vehicles have notable disadvantages, including higher upfront purchasing price, longer recharging time, and most significantly, lower driving ranges. All these challenges can potentially result in increased overall operational costs for logistics companies. This thesis proposes a comprehensive optimization modeling framework for electric freight transportation system planning and operations with …


Selection And Clustering For Disease Associated Genetic Variants, Yubo Zou Jan 2013

Selection And Clustering For Disease Associated Genetic Variants, Yubo Zou

Theses and Dissertations

Epigenetics is the study of chemical reactions, which are orchestrated for the development and maintenance of an organism. Genetic or epigenetic variants (GEVs) encompass different types of genetic measures, such as Deoxyribonucleic acid (DNA) methylation at different CpG sites, expression level of genes, or single nucleotide polymorphisms (SNPs). With the development of technology, huge amount of genetic and epigenetic information is produced. However, the rich information potentially brings in challenges in data analyses. Thus it is necessary to reduce the dimension of data to improve efficiency. In my dissertation, I will focus on two directions of dimension reduction: variable selection …