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Full-Text Articles in Engineering

Analysis And Optimization Of Colorimetric Nanosensors For Rapid Detection Of Microbes In Water, Ruby A. Lang Jun 2020

Analysis And Optimization Of Colorimetric Nanosensors For Rapid Detection Of Microbes In Water, Ruby A. Lang

Master's Theses

Access to safe water is a basic human right recognized by the United Nations General Assembly in 2010 (WHO, 2020). However, a least 2.2 billion people globally still are without safely managed water services meaning they use a drinking water source that can be contaminated with faeces (WHO, 2020). With such a pressing global health issue, it is clear that improvement to water systems is important and required in the Agenda 2030 Sustainable Development Goals (SDGs). However, to improve water systems and prove they are safe water sources, water quality testing must occur. A solution to this issue is the …


Light Downshifting Zinc Oxide-Ethylene Vinyl Acetate Nanocomposite Greenhouse Films, David V. Hiscott Mar 2020

Light Downshifting Zinc Oxide-Ethylene Vinyl Acetate Nanocomposite Greenhouse Films, David V. Hiscott

Electronic Thesis and Dissertation Repository

One method to increase the productivity of greenhouse agriculture is to increase the amount of photosynthetically available light within. This was accomplished through the use of nanocomposite greenhouse film comprised of light downshifting zinc oxide quantum dots and ethylene vinyl acetate copolymer. As this material will be used on a commodity scale, two different approaches – a large batch process and continuous plug flow reactor – were designed for mass production of zinc oxide. A design of experiment was performed to determine which synthesis parameters contribute more strongly to the quantum dot’s growth. This was done for a small-scale batch …


Investigation On Nanoparticle Based Combination Therapy For Targeted Cancer Treatment, Muhammad Raisul Abedin Jan 2020

Investigation On Nanoparticle Based Combination Therapy For Targeted Cancer Treatment, Muhammad Raisul Abedin

Doctoral Dissertations

“The current treatment methods in cancer are associated with toxicity in healthy tissues, partial therapeutic response, drug resistance and finally recurrence of the disease. The cancer drugs are challenged by non-specific binding, undesired toxicity in healthy cells, low therapeutic index and finally poor therapeutic outcome. In this work, a targeted nanoscale therapeutic system Antibody Drug Nanoparticle (ADN) was engineered to selectively inhibit the breast cancer cell growth with reduced toxicity in healthy cells. The ADNs were designed by synthesizing rod shaped anoparticles using pure chemotherapeutic drug and covalently conjugating a therapeutic monoclonal antibody (mAb) on the surface of the drug …