Engineering Commons^™

In Vivo Biosynthesis Of Inorganic Nanomaterials Using Eukaryotes - A Review, Ashiqur Rahman, Julia Lin, Francisco E. Jaramillo, Dennis A. Bazylinski, Clayton Jeffryes, Si Amar Dahoumane

Life Sciences Faculty Research

Bionanotechnology, the use of biological resources to produce novel, valuable nanomaterials, has witnessed tremendous developments over the past two decades. This eco-friendly and sustainable approach enables the synthesis of numerous, diverse types of useful nanomaterials for many medical, commercial, and scientific applications. Countless reviews describing the biosynthesis of nanomaterials have been published. However, to the best of our knowledge, no review has been exclusively focused on the in vivo biosynthesis of inorganic nanomaterials. Therefore, the present review is dedicated to filling this gap by describing the many different facets of the in vivo biosynthesis of nanoparticles (NPs) using living eukaryotic …

Novel Low Shear 3d Bioreactor For The Scaled Production Of High Purity Human Mesenchymal Stem Cells, Andrew Burns

KGI Theses and Dissertations

Human mesenchymal stem cells are an ideal candidate for stem cell therapies. They have been researched since the 1960’s and can differentiate into many desired functional cell types without undergoing teratogenesis. However, higher yields are needed for a marketable, successful stem cell therapy. To accomplish this, cells will have to be cultured to expand them to therapeutically relevant dosages for multiple patients. Bioreactor production is an ideal method to solve this problem.

The aim of this thesis is to test and validate a novel bioreactor for the cultivation of human mesenchymal stem cells. In this work, we investigate a novel …

Algae To Propellants: Biosynthesis Of 1,2-Propanediol From Algal Derived Sugars, Lauren Rachelle Merriman

Graduate Theses and Dissertations

Propylene glycol dinitrate (PGDN) is an important component used in the formulation of energetic materials. A renewable, environmentally-friendly and effective production technique for the production of 1,2-propanediol, an important precursor to PGDN, is desired. While fermentation of 1,2-propanediol has been achieved, it suffers from major limitations such as expensive feed sugars and relatively low yields. It is hypothesized that algae sugars could serve as a feedstock for the microbial synthesis of 1,2-propanediol, thereby reducing production costs and enhancing sustainability.

Algal biomass produced from an Algal Turf Scrubber® has proven to have significant potential as a source of fermentable materials. However, …

The Importance Of Emerging Biobased Industries To Engineering And Technology, Kurt A. Rosentrater, R. Balamuralikrishma

Kurt A. Rosentrater

Our society has developed an insatiable demand for energy and material goods. Historically, these needs have been met primarily by fossil fuels and other non-renewable raw materials. As environmental concerns grow, however, renewable resources are gaining increased attention. This paper examines the emergence and importance that biobased industries are increasingly beginning to play. A biobased enterprise, similar in concept to a traditional refinery or factory, utilizes conversion technologies to produce various products. These operations are rapidly increasing both in number as well as in capacity throughout this country, and are poised to add significantly to the nation’s energy and material …

The Global Relevance Of Bio-Based Industries To Engineering And Technology Education, Kurt A. Rosentrater, Radha Balamuralikrishma

Kurt A. Rosentrater

The society in which we live has developed an insatiable demand for energy and material goods. In particular, recent data reveals that the aggressive pursuit of improved standards of living in the highly populated countries of India and China has contributed to increased demand for fossil fuels, which has exacerbated the recent spike in energy costs. Historically, these needs have been met primarily by fossil fuels and other non-renewable raw materials. As environmental concerns grow, however, renewable resources are gaining increased attention. This paper examines the emergence and importance that bio-based industries are increasingly beginning to play. A bio-based enterprise, …