Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 4 of 4
Full-Text Articles in Engineering
Longitudinal Case-Control Study Of Mammographic Breast Tissue Subtypes, Kendra Batchelder
Longitudinal Case-Control Study Of Mammographic Breast Tissue Subtypes, Kendra Batchelder
Electronic Theses and Dissertations
Breast density is a known risk factor for breast cancer. However, there has been limited research on potential subtypes of mammographic dense breast tissue to identify areas of active dense tissue that is structurally reorganizing and links to cancer dynamics, versus areas of passive dense tissue which remains organized. We hypothesize that the amounts of subtypes of mammographic dense tissue and the associated rate of change through time could provide insights into breast cancer risk. A retrospective study was conducted to investigate breast cancer using longitudinal screening mammograms and accompanying pathology reports collected in 2015. Patients were matched by age …
Hybrid Power Spectral And Wavelet Image Roughness Analysis, Basel White
Hybrid Power Spectral And Wavelet Image Roughness Analysis, Basel White
Electronic Theses and Dissertations
The Two-Dimensional Wavelet Transform Modulus Maxima (2D WTMM) sliding window methodology has proven to be a robust approach, in particular for the extraction of the Hurst (H) roughness exponent from grayscale mammograms. The power spectrum is a computational analysis based on the Fourier transform that can be used to estimate the roughness of a scale-invariant image or region via the calculation of H. We aim to examine how the calculation of H in fractional Brownian motion (fBm) images and mammograms can be improved. fBm images are generated for H ∈ [0.00,1.00] for testing through the previous 2D …
Mechanical Design Of A Microwave Imaging Device For Breast Cancer Detection In Mri Scanners, Grace M. Player
Mechanical Design Of A Microwave Imaging Device For Breast Cancer Detection In Mri Scanners, Grace M. Player
Dartmouth College Master’s Theses
This project seeks to develop an updated version of a microwave imaging device for use in conjunction with breast MRI, improving upon existing technology and developing novel concepts for the device. It posits three primary redesign targets for updating the previous system: resizing the system height, making the device more iteration- friendly, and improving the overall manufacturability of the device by replacing custom components with commercially available alternatives. All three of these redesign targets are met in the new design, V2.0. The height is reduced by reducing antenna travel and height, embedding some components, and shortening the tank wall, resulting …
Impacts Of Diverse Inflammatory Stimuli On Neutrophil Behavior: Extracellular Vesicles, E-Cigarettes, And Nanoparticles, Hunter T. Snoderly
Impacts Of Diverse Inflammatory Stimuli On Neutrophil Behavior: Extracellular Vesicles, E-Cigarettes, And Nanoparticles, Hunter T. Snoderly
Graduate Theses, Dissertations, and Problem Reports
Neutrophils are the body’s front-line defenders against foreign insult and are key players in a variety of inflammatory conditions. This body of work examines the role of neutrophils in promoting pathology in three distinct inflammatory contexts. In the pro-inflammatory state provoked by breast cancer, neutrophils decondense their nuclei and release cytotoxic web-like structures known as neutrophil extracellular traps (NETs). NETs form most commonly via histone modifications facilitated by the enzyme PAD4. NETs are known to be a harbinger of disease progression and promote metastasis through capture of circulating tumor cells. It was hypothesized that breast tumors release small particles known …