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Biomedical Engineering and Bioengineering

2015

Wright State University

Antibiotic Resistance

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Full-Text Articles in Engineering

Silver Nanoparticles: The Immediate Benefits Of Low Bacterial Resistance And The Long-Term Risk Of Persistent Stress In Mammalian Cells, David Harold Ellis Jan 2015

Silver Nanoparticles: The Immediate Benefits Of Low Bacterial Resistance And The Long-Term Risk Of Persistent Stress In Mammalian Cells, David Harold Ellis

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Silver nanoparticles (AgNPs) are the fastest growing sector of nanotechnology, due mostly to their antibacterial properties. The antibacterial effectiveness of AgNPs is well known and derives from the shedding of silver ions which have multiple antibacterial targets in the bacterial cell. Due to their continuous release of ions and demonstrated antibacterial potency, some predict that AgNPs have a low potential for resistance development, which would make them a valuable asset in wound management. The ability for AgNPs to cause oxidative imbalance in mammalian cells is also well known, but the potential long-term impact of such a stress has not been …