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Full-Text Articles in Engineering
Tumor-Microenvironment-On-Chip To Mimic Tumor Heterogeneity, Victoria Noe-Kim, Altug Ozcelikkale, Bumsoo Han
Tumor-Microenvironment-On-Chip To Mimic Tumor Heterogeneity, Victoria Noe-Kim, Altug Ozcelikkale, Bumsoo Han
The Summer Undergraduate Research Fellowship (SURF) Symposium
Ductal Carcinoma In Situ (DCIS) is a non-invasive cancer that forms around breast milk ducts that can potentially progress into invasive breast cancer if untreated. Lack of models to study its diverse pathophysiology and differential response to treatments poses a challenge to develop standard treatment modalities with improved therapeutic outcomes. The traditional in vitro models such as cell monolayer are convenient but insufficient to represent the physiological characteristics of DCIS tumor microenvironment and often fail to predict clinical outcomes. The animal models effectively simulate the in vivo environment but also lack the ability to control the environmental parameters to match …
Field Penetration In Mri-Based Breast Models: A Numerical Investigation, Giuseppe Ruvio, Raffaele Solimene, Antonio Cuccaro, Max Ammann
Field Penetration In Mri-Based Breast Models: A Numerical Investigation, Giuseppe Ruvio, Raffaele Solimene, Antonio Cuccaro, Max Ammann
Articles
The use of reliable computational tools is fundamental to investigate different aspects of microwave breast cancer imaging. From the development of high-definition and realistic numerical breast models, different coupling mechanisms and the reaction of different tissues to microwave signals can be characterized. In this paper, field penetration inside four numerical breast phantoms with varying adipose content is evaluated in the frequency range 0.5 - 10 GHz across sagittal cuts.