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Full-Text Articles in Engineering
Synthesis And Characterization Of Novel Temperature-Responsive Dendritic Peg-Pdlla Star Polymers For Drug Delivery, Arunvel Kailasan
Synthesis And Characterization Of Novel Temperature-Responsive Dendritic Peg-Pdlla Star Polymers For Drug Delivery, Arunvel Kailasan
Theses and Dissertations
This study describes a novel thermoresponsive dendritic polyethylene glycol-poly(D, L-lactide) (PEG-PDLLA) core-shell nanoparticle with potential for drug delivery and controlled release. A series of dendritic PEG-PDLLA nanoparticles were synthesized through conjugation of PEG to Starburst™ polyamidoamine (PAMAM) dendrimer G3.0 and subsequent ring-opening polymerization of DLLA, in which PEG chain length (i.e., MW=1500, 6000 or 12000 Dalton) was varied; however, the feeding molar ratio of DLLA monomers to the overall PEG repeat units on the dendrimer surface was kept at 1:1. Linear PEG-PDLLA copolymers were also syntheiszed under the same condition and used as control. According to our results, dendritic PEG-PDLLA …
Biomimic Fabrication Of Electrospun Nanofibers With High-Throughput, Ji-Huan He, Yong Liu, Lan Xu, Jian-Yong Yu, Gang Sun
Biomimic Fabrication Of Electrospun Nanofibers With High-Throughput, Ji-Huan He, Yong Liu, Lan Xu, Jian-Yong Yu, Gang Sun
Ji-Huan He
Spider-spun fiber is of extraordinary strength and toughness comparable to those of electrospun fiber, the later needs a very high voltage (from several thousands voltage to several ten thousands voltages) applied to water-soluble protein “soup” that was produced by a spider, furthermore, its mechanical strength dramatically decreases comparable to spider silk. A possible mechanism in spider-spinning process is given, the distinct character in spider-spinning is that its spinneret consists of millions of nano scale tubes, and a bubble can be produced at the apex of each nano-tube. The surface tension of each bubble is extremely small such that it can …
Controlling Numbers And Sizes Of Beads In Electrospun Nanofibers, Yong Liu, Ji-Huan He, Jian-Yong Yu, Hong-Mei Zeng
Controlling Numbers And Sizes Of Beads In Electrospun Nanofibers, Yong Liu, Ji-Huan He, Jian-Yong Yu, Hong-Mei Zeng
Ji-Huan He
Abstract BACKGROUND: Electrospinning is a powerful and effective method to produce nanofibers. Beads have been observed widely in electrospun products, but effects of solvents, weight concentrations and salt additives on the number and morphology of beads in the electrospinning process have not been systematically studied. RESULTS: Both theoretical analysis and experimental results show that beads strongly depend upon solvents, weight concentrations and salt additives. Either a suitable weight concentration or a suitable salt additive can completely prevent the occurrence of beads in the electrospinning process; solvents can affect the number of beads and the morphology of electrospun fibers. CONCLUSION: Beads …
A New Resistance Formulation For Carbon Nanotubes, Ji-Huan He
A New Resistance Formulation For Carbon Nanotubes, Ji-Huan He
Ji-Huan He
A new resistance formulation for carbon nanotubes is suggested using fractal approach. The new formulation is also valid for other nonmetal conductors including nerve fibers, conductive polymers, and molecular wires. Our theoretical prediction agrees well with experimental observation.
Non-Ionic Surfactants For Enhancing Electrospinability And For The Preparation Of Electrospun Nanofibers, Shu-Qiang Wang, Ji-Huan He, Lan Xu
Non-Ionic Surfactants For Enhancing Electrospinability And For The Preparation Of Electrospun Nanofibers, Shu-Qiang Wang, Ji-Huan He, Lan Xu
Ji-Huan He
Abstract BACKGROUND: Electrospinning is widely used to produce nanofibers; however, not every polymer can be electrospun into nanofibers. To enhance electrospinability, much effort has been made in designing new apparatus, such as vibration-electrospinning, magneto-electrospinning and bubble-electrospinning. RESULTS: A representative non-ionic surfactant, TritonR X-100, is used to enhance electrospinability. The surfactant is added to an electrospun poly(vinyl pyrrolidone) polymer solution, and a dramatic reduction in surface tension is observed. As a result, a moderate voltage is needed to produce fine nanofibers, which are commonly observed during the conventional electrospinning procedure only at elevated voltage. CONCLUSION: The novel strategy produces smaller nanofibers …
Electrospinning: A Promising Technology For Discontinuous And Continuous Nanofibers, Ji-Huan He
Electrospinning: A Promising Technology For Discontinuous And Continuous Nanofibers, Ji-Huan He
Ji-Huan He
No abstract provided.